Results 81 to 90 of about 1,372,433 (300)

Phase-space shapes of clusters and rich groups of galaxies [PDF]

, 2013
Clusters and groups of galaxies are highly aspherical, with shapes approximated by nearly prolate ellipsoids of revolution. An equally fundamental property is the shape of these objects in velocity space which is the anisotropy of the global velocity ...
Wojtak, Radoslaw
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

High-resolution 3D S-wave velocity structure in northwestern Sichuan-Yunnan Block derived from ambient noise tomographyKey points

Earthquake Science
The Sichuan-Yunnan Block is located on the southeastern margin of the Qinghai-Xizang Plateau and has frequent seismic activity on the western border, posing a potential threat to human society and economic development.
Shanshan Jia, Laiyu Lu, Yutao Shi, Pingping Wu, Lijun Chang   +4 more
doaj   +1 more source

The Many Phases of Holographic Superfluids

, 2010
We investigate holographic superfluids in AdS_{d+1} with d=3,4 in the non-backreacted approximation for various masses of the scalar field. In d=3 the phase structure is universal for all the masses that we consider: the critical temperature decreases as
Chethan Krishnan, CP Herzog, CP Herzog, CP Herzog, D Arean, D Marolf, Daniel Arean, E Witten, GT Horowitz, GT Horowitz, H Elvang, H Elvang, H Iguchi, IR Klebanov, J Evslin, J Sonner, J Sonner, JM Maldacena, K Izumi, K Maeda, M Ammon, M Montull, P Basu, P Basu, P Basu, Pallab Basu, SA Hartnoll, SA Hartnoll, SS Gubser, SS Gubser, SS Gubser, T Albash, V Keranen, V Keranen, VE Hubeny, Y Brihaye   +35 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Study of Love Waves in a Heterogeneous Viscoporoelastic Layer Overlying a Viscoporoelastic Half-space

International Journal of Applied Mechanics and Engineering
This research examines to study the Love-type surface waves move through a heterogeneous layer of viscoporoelastic material that rests on a viscoporoelastic half-space.
Radhika Nagapuri, Rajitha Gurijala, Archana Reddy R, Malla Reddy Perati   +3 more
doaj   +1 more source

On the effects of self- and cross-phase modulation on photon purity for four-wave mixing photon-pair sources

, 2015
We consider the effect of self-phase modulation and cross-phase modulation on the joint spectral amplitude of photon pairs generated by spontaneous four-wave mixing. In particular, the purity of a heralded photon from a pair is considered, in the context
Bell, Bryn, McCutcheon, Will, McMillan, Alex, Rarity, John   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysis of Telegraph Equation for Propagating Waves with Dispersion and Attenuation

Foundations
The structural vibration of industrial droplet dispensers can be modeled by telegraph-like equations to a good approximation. We reinterpret the telegraph equation from the standpoint of an electric–circuit system consisting of an inductor and a resistor,
Hyoung-In Lee, Sang-Hyeon Kim, Tae-Yeon Kim, Hee-Jeong Moon   +3 more
doaj   +1 more source