Results 51 to 60 of about 1,320 (265)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

A Phasor Estimation Algorithm Based on Iterative Filtering to Remove the Decaying Direct Current Component

IEEE Access
With the large-scale use of power electronic devices, the alternating current side of the system produces decaying direct current components, greatly reducing the performance of the phasor estimation algorithms.
Pengcheng Xiang, Dengwei Duan, Xiaokun Zhao, Xiantao Zhang, Xilu Zheng, Hang Zou, Jike Wu, Xueying Liu   +7 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Optimal PMU Placement Considering Load Loss and Relaying in Distribution Networks

IEEE Access, 2018
This paper studies the problem of optimal phasor measurement unit (PMU) placement considering the constraints of full system observability and load loss.
Zhi Wu, Xiao Du, Wei Gu, Yafei Liu, Ping Ling, Jinsong Liu, Chen Fang   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Technique for pre-compliance testing of phasor measurement units [PDF]

International Journal of Electrical Power & Energy Systems, 2018
Abstract This paper introduces a technique for ‘pre-compliance’ testing of Phasor Measurement Units (PMUs) against the dynamic requirements of the IEEE C37.118.1-2014 standard, which include dynamic and steady-state test scenarios. The tests described are a necessary, but not complete, requirement for passing the IEEE standard and quickly highlight ...
Brogan, Paul V., Laverty, David M., Zhao, Xiaodong, Hastings, John, Morrow, D John, Vanfretti, Luigi   +5 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Penempatan Optimal Phasor Measurement Unit (PMU) dengan Integer Programming

Jurnal Teknik ITS, 2013
Phasor Measurement Unit (PMU) merupakan peralatan yang mampu memberikan pengukuran fasor tegangan dan arus secara real-time. PMU dapat digunakan untuk monitoring, proteksi dan kontrol pada sistem tenaga listrik.
Yunan Helmy Amrulloh
doaj  

Experimental Quantification of Hardware Requirements for FPGA-Based Reconfigurable PMUs

IEEE Access, 2019
Phasor Measurement Units (PMUs) are becoming intrinsic components of modern power systems. The synchrophasor estimation algorithms in PMUs pose stringent computational demands, which makes the application of Field Programmable Gate Arrays (FPGA) highly ...
Prottay M. Adhikari, Hossein Hooshyar, Luigi Vanfretti   +2 more
doaj   +1 more source