Results 51 to 60 of about 3,894 (208)

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

Medicinal Research Reviews, Volume 45, Issue 5, Page 1423-1451, September 2025.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra, Zoltán Mucsi, Janez Ilaš, Petra Dunkel   +3 more
wiley   +1 more source

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core  

Photocatalytic fluoroalkylation reactions of organic compounds [PDF]

, 2015
Photocatalytic methods for fluoroalkyl-radical generation provide more convenient alternatives to the classical perfluoroalkyl-radical (Rf) production through chemical initiators, such as azo or peroxide compounds or the employment of transition metals ...
Barata Vallejo, Sebastian, Bonesi, Sergio Mauricio, Postigo, Jose Alberto   +2 more
core   +1 more source

Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review

Electrochemical Science Advances, Volume 5, Issue 4, August 2025.
ABSTRACT Catalytic hydrogenation refers to the (often) metal‐mediated addition of dihydrogen (H2) equivalents to unsaturated compounds to form new element‐hydrogen bonds. This conceptually simple reaction is ubiquitous in the production of a vast number of essential chemicals.
Esteban Garcia‐Torres, David E. Herbert   +1 more
wiley   +1 more source

An Efficient Synthesis of (NH)-Phenanthridinones via Ligand-Free Copper-Catalyzed Annulation [PDF]

[[journaltype]]國外[[incitationindex]]SCI[[ispeerreviewed]]
謝仁傑
core   +1 more source

Leveraging Tumor Microenvironment to Boost Synergistic Photodynamic Therapy, Ferroptosis Anti‐Tumor Efficiency Based on a Functional Iridium(III) Complex

Advanced Science, Volume 12, Issue 14, April 10, 2025.
Ingenious introduction of an imine bond into an Ir(III)‐ferrocene complex effectively disrupts the photoinduced electron transfer process. Allowing full use of the TME to boost the efficacy of PDT, the molecule releases the Ir(III) complex and ferrocene with synergistic enhanced therapeutic effects of PDT and ferroptosis.
Yu Pei, Yinzhen Pan, Zhijun Zhang, Jun Zhu, Yan Sun, Qian Zhang, Dongxia Zhu, Guangzhe Li, Martin R. Bryce, Dong Wang, Ben Zhong Tang   +10 more
wiley   +1 more source

A terc-amino effektus vizsgálata és kiterjesztése: új típusú, biológiailag aktív policiklusos vegyületek előállítása = The study and the extension of the tert-amino effect: Synthesis of new types of polycyclic compounds with biological activities [PDF]

, 2013
1. Vizsgáltuk a terc-amino effektus 2. típusának kiterjesztését a reakcióban résztvevő vinil és terc-amino csoportot két külön gyűrűn tartalmazó (kondenzált) bi- és triaril - bifenil/fenilpiridazin, trifenil/difenilpiridazin, naftalin illetve ...
Balogh, Balázs, Czompa, Andrea, Dunkel, Petra, Halászné Dajka, Beáta, Krajsovszky, Gábor, Mátyus, Péter, Tapolcsányi, Pál, Túrós, György István, Éliás, Olivér   +8 more
core  

Label‐Free 3D Cell Imaging Using Hydrogels Functionalized with Switchable Iridium Complexes

Chemistry – A European Journal, Volume 31, Issue 19, April 1, 2025.
A label‐free imaging of cells in a 3D scaffold was achieved using switchable Ir‐complexes, covalently linked to a hydrogel. The presence of unstained cells induces the “switch‐on” of the luminescence from the Ir‐complexes, allowing clear visualization of living cells.
Federica Fiorini, Elena Longhi, Ariadna Lazaro, Daria Di Prisco, Giulia Tamboia, Giuseppe Alonci, Luigi Menduti, Luisa De Cola   +7 more
wiley   +1 more source

Mapping the Chemodiversity, Antioxidant and Enzyme Inhibitory Potential and In Silico Studies of Heliotropium europaeum

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This study established a foundation for utilizing these results and compounds as drug leads ‐ for exploring the industrial applications of Heliotropium europaeum in developing products aimed at non‐communicable diseases. ABSTRACT The annual plant Heliotropium europaeum grows in waste ground next to agricultural land and along roadsides from June to ...
Shabnam Mustafa, Muhammad Imran Tousif, Naheed Raiz, Muhammad Saleem, Saba Tauseef, Gokhan Zengin, Laiba Hassan, Areeba Hassan, Mamona Nazir, Shabbir Muhammad   +9 more
wiley   +1 more source

Covalent Organic Frameworks for Photocatalytic Hydrogen Peroxide Evolution

Chemistry – A European Journal, Volume 31, Issue 15, March 12, 2025.
Τhis Review presents a comprehensive overview of the very recent developments on COF‐based photocatalysts for H2O2 evolution. First, neat COFs with variable architecture are critically explored, followed by the presentation of the most promising hybrid COF‐based heterojunctions.
Andreas Katsamitros, Antonios N. Giannakakis, Nikolaos Karamoschos, Nikolaos Karousis, Dimitrios Tasis   +4 more
wiley   +1 more source