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Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation. [PDF]
Zhao F +8 more
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Switching Shapes: Reversible Three Species Photoisomerization of Substituted 1,2-Dihydro-1,2-azaborinines. [PDF]
Biebl SM +6 more
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Antimalarial benzo[c]phenanthridines
Bioorganic & Medicinal Chemistry Letters, 2005Analogues of the antimalarial alkaloid nitidine have been prepared with high potency against both chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. Simple modifications, using an established synthetic route, resulted in an analogue with IC(50) below 5ng/mL against a chloroquine-sensitive strain of P. falciparum.
James M, Nyangulu +7 more
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Phenanthridine alkaloids from Zanthoxylum madagascariense
Fitoterapia, 2005Four benzo[c]phenanthridine alkaloids have been isolated from the stem bark of Zanthoxylum madagascariense. These compounds were identified by extensive use of NMR spectroscopy.
M T, Martin +2 more
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Synthesis of Phenanthridine Derivatives via Photolysis
The Journal of Organic Chemistry, 2011An improved photochemical method for producing the prolifically bioactive phenanthridine system is reported. A wide variety of derivatives were obtained in two steps in yields ranging from 31 to 95%.
Linsenmeier, A. +2 more
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SYNTHESES INVOLVING IMIDOGEN INTERMEDIATES: PHENANTHRIDINES AND BENZO[c]PHENANTHRIDINES
Canadian Journal of Chemistry, 1963not available
R. A. Abramovitch +2 more
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Thiophene Analogus of Phenanthridine
Synthetic Communications, 1972Abstract We reported reoently1 that the dithienpyridones I-III could be prepared by the cyclisation of the appropriate dithienylazides.
G. J. Heeres, Hans Wynkrg
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Acridities and phenanthridines
2020The acridine and phenanthridine chromophores both contain a central six-membered aromatic nitrogen heterocycle, with benzo rings fused onto each side. Although sulfonated and hydroxylated acridines have been synthesized, none are used as stains. The hydrophilic/lipophilic properties of the dyes under usage conditions are varied.
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