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Electro-Oxidative Synthesis of Phenazines

Organic Letters, 2023
We disclose herein electro-oxidative synthesis as the general protocol for procuring phenazines under mild reaction conditions. Using aerial oxygen as an oxidant, inexpensive electrolyte, and electrodes, a diverse range of phenazines have been accessed in good yields via the ring contraction of 10,11-dihydro-5H-dibenzo[b,e][1,4]diazepines. In addition,
Deepak Sharma   +2 more
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Phenazines and Benzcinnolines

Nature, 1947
A number of attempts have been made to devise general methods for the synthesis of phenazines1,2,3; but in a series of researches carried out during 1945–46 we found that most of the well-known methods failed in the case of some di-alkoxyphenazines. On the other hand, comparatively good results were obtained using the little-known reaction of Waterman ...
P. Z. SLACK, R. SLACK
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Structure of phenazine

Acta Crystallographica Section C Crystal Structure Communications, 1991
C 12 H 8 N 2 cristallise dans P2 1 /n avec a=7,083, b=5,072, c=12,794 A, β=102,34 o , Z=2; affinement jusqu'a R=0,0532. La structure comprend des molecules de phenazine orientees autour d'un centre de symetrie.
K. Woźniak, B. Kariuki, W. Jones
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Hepatitis C viral IRES inhibition by phenazine and phenazine-like molecules

Bioorganic & Medicinal Chemistry Letters, 2000
An in vitro assay based on the expression of Fluci reporter gene under the translational control of HCV IRES was used to evaluate and screen compound libraries. A structure-activity relationship study on a phenazine hit was conducted. Our data suggest that an intact phenazine or phenazine-like core with two distal polar substitutions is crucial for ...
W, Wang   +5 more
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Synthese einiger Phenazin‐Derivate

Chemische Berichte, 1952
AbstractEs wird die Darstellung des 1‐Oxymethyl‐phenazins durch Reduktion des Phenazin‐carbonsäure‐(1)‐methylesters beschrieben. Durch Oxydation des 1‐Oxymethyl‐phenazins gelangt man zu dem Phenazin‐aldehyd‐(1), der auch durch Reduktion des Phenazin‐carbonsäure‐(1)‐dimethylamids mit Lithiumaluminiumhydrid erhalten wird.
Birkofer, L., Birkofer, A.
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The Biosynthesis of Phenazines

2013
The phenazines are nitrogen-containing colored aromatic secondary metabolites that many bacterial species produce and excrete into the environment, sometimes in such large quantities that they are visible to the naked eye. Phenazines act as broad-specificity antibiotics and as virulence as well as survival factors in infectious disease, which is in ...
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Resonance Energies of Acridine and Phenazine

Nature, 1946
IN the course of an investigation of the heats of combustion of a number of acridine derivatives, the heats of combustion of acridine and phenazine have been determined. From these data the resonance energies of these important heterocyclic nuclei have been calculated for the first time.
A, ALBERT, J B, WILLIS
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Biosynthesis of phenazines

The Journal of Organic Chemistry, 1972
U, Hollstein, L G, Marshall
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Phenazine Syntheses. I. Halogen-Substituted Phenazines

The Journal of Organic Chemistry, 1953
Donald L. Vivian, Jonathan L. Hartwell
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