Results 101 to 110 of about 30,643 (283)

Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents [PDF]

, 1985
Phencyclidine (PCP) was tested on the metathoracic tibialis muscles of Locusta migratoria. In physiological solution, the peak amplitude of the excitatory postsynaptic currents (EPSCs) evoked by nerve stimulation was linearly related to membrane ...
M. Idriss, E.X. Albuquerque, Johnson, Snyder, Vincent, Garey, Marwaha, Albuquerque, Albuquerque, Albuquerque, Corteggiani, Usherwood, Idriss, Idriss, Ishida, Yamamoto, Cull-Candy, Usherwood, Hoyle, Mathers, Takeuchi, Kuba, Gration, Spivak, Andersen, Adler   +25 more
core   +2 more sources

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Low dose ketamin

Bali Journal of Anesthesiology, 2017
Ketamine binds non-competitive against a phencyclidine receptors bound N-methyl-D-aspartate (NMDA), a receptor that is involved in the pathophysiology of acute pain.
Made Wiryana, I Ketut Sinardja, I Gede Budiart, Tjokorda Gde, Agung Senapathi, Made Widnyana, I Wayan Aryabiantara, I Gusti Agung Gede Utara Hartawan, Pontisomaya Parami, Ni Putu Adinda Putra Pradhana, Adinda Putra Pradhana   +10 more
doaj   +1 more source

Photoelectrochemical Charge Excitation Enhancement by Triboelectric Nanogenerator for High‐Efficiency Self‐Powered Anticorrosion

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The synergy of solar and mechanical energy enables a self‐powered photoelectrochemical cathodic protection system, which enhances carrier separation for efficient and sustainable anticorrosion. Harnessing the synergy of solar and mechanical energy presents a potential strategy for high‐efficiency photoelectrochemical cathodic protection.
Youbo Nan, Xiutong Wang, Xiaofan Zhai, Weijie Fan, Yanan Sun, Hui Zhou, Yanliang Huang   +6 more
wiley   +1 more source

Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia

Frontiers in Molecular Neuroscience, 2008
Schizophrenia is a common psychiatric disorder of high incidence, affecting approximately 1% of the world population. The essential neurotransmitter pathology of schizophrenia remains poorly defined, despite huge advances over the past half-century in ...
Colin Kehrer, Nino Maziashvili, Tamar Dugladze, Tengis Gloveli   +3 more
doaj   +1 more source

Comparison of two ketamine/xylazine anesthesic protocols in pigs (Sus crofa domestica) [PDF]

, 2018
The pig (Sus scrofa domestica) is an animal used as an experimental model in surgical procedures. This makes the use of anaesthesia necessary. The present study constitutes a comparison between two different ketamine/xylazine concentration protocols. One
Gargiulo, Pascual Angel, Giai, Marcos, Guevara, Manuel Alejandro, Lorenzo Aquaro, Sofía Ana   +3 more
core   +1 more source

Structural Design of MOF‐Based and MOF‐Derived Composites for Oxygen Evolution Electrocatalysis: Materials Innovation for Energy and Environmental Sustainability

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review provides an overview of recent developments in metal organic framework (MOF)‐based and MOF‐derived composites for efficient oxygen evolution reaction. This review also emphasizes the structural design of electrocatalyst, active site optimization, and emerging prospects of their use in practical electrolyzer systems.
Bhagyashri B. Kamble, Aditi De, Seung Joo Jang, Arun Karmkar, Venkatachalam Vinothkumar, Niyaz Mujawar, Subrata Kundu, Tae Hyun Kim   +7 more
wiley   +1 more source

Similarities in the behavior and molecular deficits in the frontal cortex between the neurotensin receptor subtype 1 knockout mice and chronic phencyclidine-treated mice: Relevance to schizophrenia

Neurobiology of Disease, 2010
Much evidence suggests that targeting the neurotensin (NT) system may provide a novel and promising treatment for schizophrenia. Our recent work shows that: NTS1 knockout (NTS1−/−) mice may provide a potential animal model for studying schizophrenia by ...
Zhimin Li, Mona Boules, Katrina Williams, Andres Gordillo, Shuhua Li, Elliott Richelson   +5 more
doaj   +1 more source

An expanding range of targets for kynurenine metabolites of tryptophan [PDF]

, 2013
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail, Stone, Trevor W., Stoy, Nicholas   +2 more
core   +1 more source

Machine learning‐based prediction of elevated N terminal pro brain natriuretic peptide among US general population

ESC Heart Failure, Volume 12, Issue 2, Page 859-868, April 2025.
Abstract Aims Natriuretic peptide‐based pre‐heart failure screening has been proposed in recent guidelines. However, an effective strategy to identify screening targets from the general population, more than half of which are at risk for heart failure or pre‐heart failure, has not been well established.
Yuichiro Mori, Shingo Fukuma, Kyohei Yamaji, Atsushi Mizuno, Naoki Kondo, Kosuke Inoue   +5 more
wiley   +1 more source