Results 41 to 50 of about 10,621 (203)

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

The effects of zinc sulfate on ethyl glucuronide immunoassay urine testing [PDF]

open access: yes, 2016
Published research in the Journal of Analytical Toxicology and the American Society for Clinical Pathology has confirmed that the presence of Zinc Sulfate in adulterated urine samples can influence the testing results using EMIT and ELISA immunoassay ...
Cawley, Shanna Marie
core   +1 more source

Differential effects of ketamine enantiomers on EEG parameters including the gamma‐delta shift phenomenon

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz   +4 more
wiley   +1 more source

Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model. [PDF]

open access: yes, 2015
Schizophrenia is a neuropsychiatric disorder affecting 1% of the world's population. Due to both a broad range of symptoms and disease heterogeneity, current therapeutic approaches to treat schizophrenia fail to address all symptomatic manifestations of ...
Bahn, Sabine   +5 more
core   +9 more sources

Recovery From Anorexia Nervosa: A Concept Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim Despite decades of research, we still know surprisingly little about how best to bring about lasting recovery from anorexia nervosa (AN). Furthermore, there is a lack of consensus in the research and treatment communities about what constitutes recovery from AN, or whether “recovery” is even an appropriate term to use in this context.
Sarah Ramsay, Kendra Allison
wiley   +1 more source

Scoping Review of Sexual and Gender Minority Health Research in Ireland

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore   +7 more
wiley   +1 more source

Psychoactive substance abuse amongst an urban secondary school population in Enugu, Nigeria: Prevalence and pattern of use

open access: yesInternational Journal of Medicine and Health Development, 1999
A survey of psychoactive substance abuse based on a random sample of 181 students was carried out using a self-report drug use questionnaire in April 1998. A general life time prevalence of 85.1% was found. However, most were occasional users.
K O B. Okonkwo   +3 more
doaj  

WORKPLACE SUBSTANCE USE, THE RISK OF OCCUPATIONAL INJURY, AND TESTING [PDF]

open access: yes, 2005
Over the past 20 years, the "workplace substance abuse prevention industry" has grown enormously in size and has become more sophisticated in its marketing approach. Drug testing alone has become a $6 billion industry.
Zimbardi, Guy
core  

Les psychotropes criminogènes [PDF]

open access: yes, 2007
Les psychotropes altèrent le psychisme d’un individu et peuvent affecter les perceptions, l’humeur, la conscience, le comportement et diverses fonctions psychologiques et physiques.
Ben Amar, Mohamed
core   +1 more source

Primary Care Utilization Among Legally Adjudicated Elder Mistreatment Cases in Comparison to Other Older Adults

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Elder mistreatment is associated with adverse health outcomes and increased Emergency Department (ED) and hospital utilization patterns in the period surrounding initial mistreatment identification. Less is known about outpatient primary care utilization, but it has been hypothesized that elder mistreatment victims may use this care
Jiani Yu   +12 more
wiley   +1 more source

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