Results 91 to 100 of about 3,571 (163)

Ligand-Promoted Iridium-Catalyzed Transfer Hydrogenation of Terminal Alkynes with Ethanol and Its Application

open access: yes, 2019
A ligand-promoted iridium-catalyzed transfer hydrogenation of terminal alkynes with ethanol and its application has been developed. Highly chemical selectivity control is achieved based on ligand regulation.
Yufeng Sun (420176)   +17 more
core   +1 more source

Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in major depressive patients. Relationship to clinical improvement.

open access: yes, 1992
We have examined the effects of two monoamine oxidase (MAO) inhibitors with different mechanisms of action--phenelzine and brofaromine--on peripheral serotonergic (5-hydroxytryptamine [5-HT]) measures, sensitive to the inhibition of MAO-A (intra- and ...
Pérez, Juana   +3 more
core  

An assessment of antidepressant like potentiality of Phyllanthus emblica on experimental rodent model of depressive disorder under the light of numerous behavioural test batteries

open access: yesJournal of Holistic Integrative Pharmacy
Objective: The unfavorable costs and effects of currently accessible antidepressant agents necessitate the development of more potent and safe alternatives, that will obviate the potential problems associated with the commercially available marketed ones.
Md. Rafat Tahsin   +9 more
doaj   +1 more source

Comparative efficacy and acceptability of pharmacological treatments for post-traumatic stress disorder in adults: a network meta-analysis.

open access: yes, 2018
BACKGROUND Guidelines about post-traumatic stress disorder (PTSD) recommend broad categories of drugs, but uncertainty remains about what pharmacological treatment to select among all available compounds.
Williams, Taryn   +8 more
core   +1 more source

Optimal treatment of social phobia: systematic review and meta-analysis

open access: yesNeuropsychiatric Disease and Treatment, 2012
John Canton, Kate M Scott, Paul GlueDepartment of Psychological Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New ZealandAbstract: This article proposes a number of recommendations for the treatment of generalized social phobia ...
Scott KM, Canton J, Glue P
doaj  

Determination of Phenelzine in Human Plasma Sample Using SPE- UPLC–MS/MS Assay

open access: yes, 2016
In this paper a Fast and highly sensitive ultra-high performance liquid chromatography (UPLC) method for the determination of phenelzine in human plasma have been developed using tandem mass spectrometry (MS/MS) detection.
Reddy, S. S. (S)   +5 more
core  

The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain

open access: yes, 1996
The increases in extracellular serotonin (5-hydroxytryptamine; 5-HT) produced by some antidepressent drugs in forebrain are attenuated by the activation of somatodendritic 5-HT1A autoreceptors by the excess 5-HT induced by these agents in the midbrain ...
Ildefonso Hervás   +5 more
core   +1 more source

Dextromethorphan-monoamine oxidase inhibitor interaction in rabbits

open access: yes, 1973
Severe toxic reactions may occur clinically when imipramine, pethidine or dextromethorphan is administered to a patient being treated with a monoamine oxidase inhibitor (MAOI).
John G Sinclair
core   +1 more source

Brain norepinephrine, dopamine, and 5-hydroxytryptamine concentration abnormalities and their role in the high seizure susceptibility of epileptic chickens

open access: yes, 1981
Norepinephrine (NE), dopamine (DA), and 5-hydroxytryptamine (5-HT) concentrations were determined in cerebral hemispheres, optic lobes, the midbrain pons–medulla, and cerebellum of adult homozygous recessive epileptic chickens during interictal periods ...
D. D. Johnson   +4 more
core   +1 more source

Pharmacological treatments for atypical depression: A systematic review and network meta-analysis of randomized controlled trials

open access: yes
Introduction: Atypical depression is a highly prevalent subtype that includes mood reactivity, hypersomnia, and leaden paralysis, necessitating different therapeutic approaches than melancholic depression.
Di Lorenzo, Chiara   +13 more
core   +1 more source

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