Results 21 to 30 of about 7,416 (225)

Synthesis and evaluation of variably substituted N-methyl tetrahydroisoquinolines and benzazepines as monoamine reuptake inhibitors

open access: yesResults in Chemistry, 2022
The use of N-methyl-1, 2, 3, 4-tetrahydroisoquinoline as pharmacophores has been studied over the years. It has a structural similarity with the N, N-dimethyl phenethylamine, a framework entrenched in the drug venlafaxine, acknowledged for its ...
Sneh Lata   +5 more
doaj   +1 more source

Recent trends in analytical methods to determine new psychoactive substances in hair [PDF]

open access: yes, 2017
New Psychoactive Substances (NPS) belong to several chemical classes, including phenethylamines, piperazines, synthetic cathinones and synthetic cannabinoids.
García Algar, Oscar   +4 more
core   +1 more source

Simultaneous Determination of 9 Biogenic Amines in Larimichthys polyactis by UHPLC-MS/MS

open access: yesShipin gongye ke-ji, 2023
To rapidly determine 9 biogenic amines including spermine, spermidine, putrescine, cadaverine, histamine, tryptamine, octopamine, tyramine and β-phenethylamine in aquatic products, the ultra high-performance liquid chromatography-tandem mass spectrometry
Zhenling LUO   +3 more
doaj   +1 more source

Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs) [PDF]

open access: yes, 2017
4-Thio-substituted phenethylamines (2C-T drugs) are potent psychedelics with poorly defined pharmacological properties. Because of their psychedelic effects, 2C-T drugs are sometimes sold as new psychoactive substances (NPSs).
Hoener, Marius C.   +3 more
core   +1 more source

Associations between classic psychedelics and nicotine dependence in a nationally representative sample

open access: yesScientific Reports, 2022
Tobacco use is the single largest cause of preventable death worldwide, but none of the established treatments aimed at smoking cessation work for a majority of smokers.
Grant Jones   +2 more
doaj   +1 more source

Population Survey Data Informing the Therapeutic Potential of Classic and Novel Phenethylamine, Tryptamine, and Lysergamide Psychedelics

open access: yesFrontiers in Psychiatry, 2020
IntroductionThe majority of contemporary psychedelic research has focused on ayahuasca, lysergic acid diethylamide, and psilocybin, though there are hundreds of novel psychedelic compounds that may have clinical utility.
James D. Sexton   +2 more
doaj   +1 more source

Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors. [PDF]

open access: yesPLoS ONE, 2013
Serotonergic ligands have proven effective drugs in the treatment of migraine, pain, obesity, and a wide range of psychiatric and neurological disorders.
Vignir Isberg   +4 more
doaj   +1 more source

Receptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs) [PDF]

open access: yes, 2015
N-2-methoxybenzyl-phenethylamines (NBOMe drugs) are newly used psychoactive substances with poorly defined pharmacological properties. The aim of the present study was to characterize the receptor binding profiles of a series of NBOMe drugs compared with
Buchy, Danièle   +5 more
core   +1 more source

Phenethylamine Does Not Accelerate Healing in Staphylococcus aureus-infected Wounds in Mice

open access: yesBiomedical Sciences and Clinical Medicine
OBJECTIVE Bacterial infections can lead to a delay in the wound healing process. Recent studies have reported that trace amines accelerate wound healing by enhancing keratinocyte migration thus promoting a faster wound re-epithelization process ...
Hana Dian Mufida   +3 more
doaj   +1 more source

Receptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines

open access: yesFrontiers in Pharmacology, 2019
Background: 2,4,5-Trimethoxyamphetamine (TMA-2) is a potent psychedelic compound. Structurally related 4-alkyloxy-substituted 2,5-dimethoxyamphetamines and phenethylamine congeners (2C-O derivatives) have been described but their pharmacology is mostly ...
Karolina E. Kolaczynska   +5 more
doaj   +1 more source

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