Results 31 to 40 of about 7,416 (225)

A simple two-step synthesis of 2-(alkylamino)-1-arylethanols, including racemic adrenaline, from aromatic aldehydes via 5-aryloxazolidines [PDF]

open access: yes, 2013
Benzaldehydes react smoothly with nonstabilized azomethine ylides, generated in situ from sarcosine/formaldehyde or N-(methoxymethyl)-N- (trimethylsilylmethyl)benzylamine, to give 5-aryloxazolidines as intermediates.
Moshkin, V. S., Sosnovskikh, V. Y.
core   +1 more source

Changes in fecal metabolic and lipidomic features by anti-TNF treatment and prediction of clinical remission in patients with ulcerative colitis

open access: yesTherapeutic Advances in Gastroenterology, 2023
Background: Therapeutic targets for ulcerative colitis (UC) and prediction models of antitumor necrosis factor (TNF) therapy outcomes have not been fully reported.
Seok-Young Kim   +26 more
doaj   +1 more source

Inhibitor specificity of amine oxidase [PDF]

open access: yes, 1943
Although at the present time it appears clear that amine oxidase oxidation of adrenalin, or other o-diphenolic pressor amines such as were studied by Richter (6), does not play a significant physiological role, it is equally clear that the inactivation ...
Alles, Gordon A., Heegaard, Erik V.
core  

Recent changes in drug abuse scenarios : The new/novel psychoactive substances (NPS) phenomenon [PDF]

open access: yes, 2018
© 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Peer ...
Schifano, Fabrizio
core   +2 more sources

Electrochemical Aptasensor for Detection of Dopamine [PDF]

open access: yes, 2020
This work presents a proof of concept of a novel, simple, and sensitive method of detection of dopamine, a neurotransmitter within the human brain. We propose a simple electrochemical method for the detection of dopamine using a dopamine-specific aptamer
Abu-Ali, Hisham   +4 more
core   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Stereochemistry of the Carbon-Nitrogen Bond Cleavage by Chloroformate Esters

open access: yesCHIMIA, 1974
Nicotine reacts with chloroformic esters to give the chloro-carbamates resulting from the cleavage of the C2' –N1' bond. The reaction is shown to proceed with at least 96 to 98 % inversion of configuration.
C. Hootelé, J.P. Lenders
doaj   +1 more source

DESIGN, SYNTHESIS, BIOLOGICAL EVALUATION, AND IN SILICO STUDY OF NOVEL UREA DERIVATIVES AS INHIBITORS OF CARBONIC ANHYDRASE AND ACETYLCHOLINE ESTERASE

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2022
This study aimed to synthesize novel unsymmetrical urea derivatives containing biologically active tryptamine and phenethylamines and investigate their inhibition effects on human carbonic anhydrase (hCA) I and II isozymes as well as ...
Yusuf AKBABA, Ramazan KALIN
doaj   +1 more source

Substrate specificity of amine oxidase [PDF]

open access: yes, 1943
The tyramine oxidase activity of liver extracts found by Hare (1), the aliphatic amine oxidase activity of brain, kidney, and liver extracts observed by Pugh and Quastel (2), and the adrenalin oxidase activity of similar extracts noted by Blaschko ...
Alles, Gordon A., Heegaard, Erik V.
core  

Small molecules as arthropod kinin receptor antagonists, feeding modulators, or novel mosquitocidal agents

open access: yesPest Management Science, EarlyView.
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos   +1 more
wiley   +1 more source

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