Results 51 to 60 of about 7,416 (225)

Plasmon-free Surface-enhanced Raman Spectroscopy on TiO\u3csub\u3e2\u3c/sub\u3e-graphene Oxide Inverse Opal Substrates [PDF]

, 2019
TiO2-graphene oxide (GO) inverse opal materials were shown to be active plasmon-free surface-enhanced Raman spectroscopy (SERS) substrates. The SERS activity of the substrates was analyzed using three different probe molecules: phenethylamine (PEA ...
Atkinson, Elizabeth J.O., Perez, Luis
core   +1 more source

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

New psychoactive substances (NPS) on cryptomarket fora: An exploratory study of characteristics of forum activity between NPS buyers and vendors [PDF]

, 2017
Background The continual diversification of new psychoactive substances (NPS) circumventing legislation creates a public health and law enforcement challenge, and one particularly challenged by availability on Hidden Web cryptomarkets.
Aldridge, Bancroft, Barratt, Barratt, Barratt, Barratt, Barratt, Broséus, Burns, Caudevilla, Caudevilla, Christin, Cox, Dolliver, Dolliver, Décary-Hétu, Eurobarometer 401, European Commission, European Monitoring Centre for Drugs and Drug Addiction, European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), European Union, Evelyn Hearne, Evrard, Global Drug Survey, Hardy, Hearne, Jeffries, Karlsson, Kjellgren, Lavorgna, Lavorgna, Marie Claire Van Hout, Martin, Martin, Martin, Martinotti, Munksgaard, Móró, Ormsby, Orsolini, Phelps, Rhumorbarbe, Rosino, Sande, Schifano, Soska, Soussan, Soussan, Soussan, Tzanetakis, UNODC, van Amsterdam, Van Buskirk, Van Buskirk, Van Hout, Van Hout, Van Hout, Van Hout, Van Hout, Werse, Zawilska   +60 more
core   +1 more source

2-Phenethylamines in Medicinal Chemistry: A Review

Molecules, 2023
A concise review covering updated presence and role of 2-phenethylamines in medicinal chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are enumerated in key therapeutic targets, listing medicinal chemistry hits and appealing screening compounds.
Carlos T. Nieto, Alejandro Manchado, Leland Belda, David Diez, Narciso M. Garrido   +4 more
openaire   +3 more sources

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

British Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck, Mario van der Stelt   +1 more
wiley   +1 more source

The Effects of Different Processing Methods on the Levels of Biogenic Amines in Zijuan Tea

Foods, 2022
This study aimed to evaluate the effects of processing methods on the content of biogenic amines in Zijuan tea by using derivatization and hot trichloroacetic acid extraction with HPLC-UV.
Dandan Liu, Kang Wang, Xiaoran Xue, Qiang Wen, Shiwen Qin, Yukai Suo, Mingzhi Liang   +6 more
doaj   +1 more source

Drugs and the internet. [PDF]

, 2013
Key findings: The number of retailers on the Silk Road increased (from 282 at time 1 to 374 at the last time point), while the number of retailers on the surface web remained relatively stable (92 at time 1 and 101 at the last time point).
Bruno, Raimondo, Burns, Lucy, Roxburgh, Amanda, Van Buskirk, Joe   +3 more
core  

Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones [PDF]

, 2018
Because of the beneficial effect of a trifluoromethyl group on the biological properties of bioactive compounds on the one hand and the versatile synthetic potential of beta-lactams on the other hand, 4-CF3-beta-lactams comprises interesting entities for
D'hooghe, Matthias, Dao Thi, Hang, Van Nguyen, Tuyen   +2 more
core   +1 more source

A Roadmap for Breeding Sweet Tomatoes

Modern Agriculture, Volume 4, Issue 1, June 2026.
This graphical abstract outlines four breeding strategies for enhancing sugar content and sweetness in tomato fruits: (1) Identification of key genes and functional variant loci regulating fruit sugar accumulation through systematic germplasm collection, genome‐wide association studies (GWAS), map‐based cloning, and reverse genetics approaches.
Jie Chen, Hongjun Lyu, Jinzhe Zhang
wiley   +1 more source