Results 181 to 190 of about 6,115 (220)

Pancreatitis and Phenformin

Annals of Internal Medicine, 1972
Excerpt To the editor: Phenformin therapy may be associated with a metallic taste, anorexia, nausea, and occasional diarrhea with abdominal cramps.
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Phenformin and lactic acidosis

Clinical Pharmacology & Therapeutics, 1966
There is considerable evidence, both from animal studies and clinical reports, to suggest that the hypoglycemic agent phenformin interferes with lactate metabolism. Experimental data are reported which are consistent with a defiCiency in the ability of phenformin‐treated rats to handle endogenous and exogenous lactate.
J, Lacher, L, Lasagna
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Lactic Acidosis and Phenformin Hydrochloride

JAMA: The Journal of the American Medical Association, 1963
Two cases of diabetic patients on phenformin (phenethylbiguanide) hydrochloride therapy in metabolic acidosis due to lactic acidosis are described. Each had hypotension due to myocardial and mesenteric infarction respectively. Significant ketosis was not present. Altered lactate metabolism has been described in diabetic patients treated with phenformin
G M, BERNIER, M, MILLER, C S, SPRINGATE
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Pharmacokinetics of Phenformin in Man

The Journal of Clinical Pharmacology, 1975
Phenformin was assayed in urine, plasma, and sputum specimens, obtained from two healthy volunteers during the four-day period following oral administration of a single therapeutic dose. Approximately one third of the drug was excreted unchanged in the urine.
D, Alkalay, L, Khemani, W E, Wagner, M F, Bartlett   +3 more
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Phenformin and Pancreatitis

Annals of Internal Medicine, 1977
Excerpt To the editor: We wish to report our experience with a patient who developed pancreatitis while using phenformin.
LAWRENCE M. RYAN, PAUL HANKWITZ, MICHAEL BANASIAK   +2 more
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Phenformin, Tetracycline and Lactic Acidosis

Annals of Internal Medicine, 1977
Excerpt To the editor: The report by Blumenthal and Streeten (Ann Intern Med84:55-56, 1976) of the association between the biguanide phenformin, the antibiotic tetracycline, and serious lactic acid...
P. J. PHILLIPS, R. W. PAIN, G. EASTERBROOK   +2 more
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Phenformin Treatment of Diabetes

JAMA: The Journal of the American Medical Association, 1971
The AMA Council on Drugs has reviewed a preliminary report of the University Group Diabetes Program (UGDP) study of phenformin as treatment of asymptomatic diabetes. The report appears elsewhere in this issue ofThe Journal(p 777). The Council concludes that the UGDP has produced no data indicating that therapy directed toward lowering the blood ...
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Attempted Suicide with Phenformin

Diabetes, 1965
Following ingestion of .85 gm. of phenformin, in a suicide attempt, the principal symptoms were violent gastrointestinal cramping, nausea, and vomiting, all of a few hours' duration. This appeared to provide major protection against other toxic effects. There was no significant hematemesis or melena.
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Phenformin Acidosis

JAMA, 1964
L, FREEDMAN, M, BLITZ
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Phenformin Acidosis

New England Journal of Medicine, 1962
A, GOTTLIEB, J, DUBERSTEIN, A, GELLER
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