Results 101 to 110 of about 34,408 (289)

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Cognitive Effects of Phenobarbital

open access: yes, 1996
Neurocognitive behavior in 9 children with various epilepsies was evaluated before and at 6 months after discontinuing phenobarbital monotherapy at the Department of Child Neurology, Instituto Nazionale Neurologico “Carlo Besta;” Milano ...
J Gordon Millichap
core   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

Withdrawal of parenteral phenobarbitone - Implications for resource-poor countries

open access: yes, 2005
Parenteral phenobarbitone is an integral part of the management of status epilepticus, especially in the context of resource-poor countries. It is highly effective at controlling seizures.
Wilmshurst, JM   +7 more
core   +1 more source

A phenobarbital overdose: a case report [PDF]

open access: yes, 2017
Background: Phenobarbital is a long-acting barbiturate, responsible for many cases of poisoning, from unintentional overdose or attempted suicide. We report a case of phenobarbital overdose in a patient with history of depression.
LICATA, Anna   +6 more
core  

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

open access: yesAdvanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu   +9 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Doctor of Pharmacy

open access: yes, 1980
dissertationOne of the first-line drugs in the therapy of seizure disorders in pediatrics is phenobarbital. Frequently it is used alone when seizures can be controlled with a single drug, however, its use in combination with other anticonvulsants is also
Davis, Anne Garrett
core  

Phenobarbital and Temperature Profile During Hypothermia for Hypoxic-Ischemic Encephalopathy

open access: yes, 2011
Data from the whole-body hypothermia trial was analyzed to examine the effects of phenobarbital administration prior to cooling (+PB) on the esophageal temperature ( Te) profile, during the induction phase of hypothermia.
Michele C. Walsh   +10 more
core   +1 more source

Use of Phenobarbital in Delirium Tremens

open access: yes, 2017
The standard of care for alcohol withdrawal centers on the use of escalating doses of benzodiazepines until clinical improvement is achieved. However, there is no established standard in the care of patients with severe alcohol withdrawal and delirium ...
Jeffrey Fujimoto   +2 more
core   +2 more sources

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