Phenobarbital and Temperature Profile During Hypothermia for Hypoxic-Ischemic Encephalopathy
Data from the whole-body hypothermia trial was analyzed to examine the effects of phenobarbital administration prior to cooling (+PB) on the esophageal temperature (T e) profile, during the induction phase of hypothermia.
G. Sant’Anna+10 more
semanticscholar +1 more source
PHENOBARBITAL-INDUCED SYNTHESIS OF THE MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM AND ITS RELATIONSHIP TO THE PROLIFERATION OF ENDOPLASMIC MEMBRANES [PDF]
Sten Orrenius+2 more
openalex +1 more source
Wang et al. discover a novel lncRNA regulator of mutant oncoprotein which prevents AKT1E17K dephosphorylation. SVIL‐AS1 overexpression correlates with poor prognosis of breast cancer patients. It interacts with AKT1E17K protein and impedes PP2A holoenzyme from dephosphorylating AKT1 by blocking the binding of the regulatory subunit PPP2R2A to AKT1 ...
Jingyi Wang+8 more
wiley +1 more source
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen+3 more
core +1 more source
Epilepsy beyond seizures: a review of the impact of epilepsy and its comorbidities on health-related quality of life in dogs [PDF]
Epilepsy is one of the most common chronic neurological conditions in the dog, estimated to affect 0.6 to 0.75 per cent of dogs. Owners of dogs with epilepsy have previously indicated that their dog's quality of life (QoL) is of greatest importance to ...
Packer, R M A, Volk, H A
core +1 more source
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li+6 more
wiley +1 more source
Multiple Sampling Capsule Robot for Studying Gut Microbiome
A multiple sampling capsule robot (MSCR) is developed for longitudinal gut microbiome analysis. Employing electromagnetic field control, the MSCR can locomote actively, precisely align the selected channel, and collect up to six microbiome samples with minimal cross‐contamination.
Sanghyeon Park+3 more
wiley +1 more source
HETEROGENEITY OF ROUGH-SURFACED LIVER MICROSOMAL MEMBRANES OF ADULT, PHENOBARBITAL-TREATED, AND NEWBORN RATS [PDF]
Gustav Dallner+2 more
openalex +1 more source
INCREASE IN LEVELS OF GLUCURONYLATING ENZYMES AND ASSOCIATED RISE IN ACTIVITIES OF MITOCHONDRIAL OXIDATIVE ENZYMES UPON PHENOBARBITAL ADMINISTRATION IN THE RAT [PDF]
Phillip Zeidenberg+2 more
openalex +1 more source
Dupuytren's contracture as result of prolonged administration of phenobarbital. [PDF]
Dupuytren's disease is a fibroproliferative condition involving the superficial palmar fascia, leading to a progressive and irreversible flexion of the fingers.
CORDOVA, Adriana+2 more
core