Results 11 to 20 of about 29,842 (147)

Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit

BMC Pediatrics, 2018
Background Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication.
Tamorah Lewis, Simisola Kuye, Ashley Sherman   +2 more
doaj   +1 more source

Evading Seizures: Phenobarbital Reintroduced as a Multifunctional Approach to End-of-Life Care

Case Reports in Oncology, 2022
The selected case study aimed to evaluate the role of phenobarbital as a drug of choice in end-of-life (EOL) settings. Phenobarbital is efficacious in management of EOL seizures and agitation, can be easily administered via different modes, and utilized ...
Helen Senderovich, Sarah Waicus, Keisa Mokenela   +2 more
doaj   +1 more source

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

Brazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the ...
C.M. Yokoro, S.M.S. Pesquero, R.M.M. Turchetti-Maia, J.N. Francischi, M.A.K.F. Tatsuo   +4 more
doaj   +1 more source

Phenobarbital-induced autoimmune haemolytic anaemia, thrombocytopenia and peripheral lymphadenomegaly due to reactive lymphoid hyperplasia in a cat

Journal of Feline Medicine and Surgery Open Reports, 2022
Case summary A female neutered domestic longhair cat, aged 1 year and 5 months, presented with lymphadenomegaly and anaemia following therapy with phenobarbital for idiopathic epilepsy.
Michelle Walton-Clark, Victoria Travail, Matthew Best   +2 more
doaj   +1 more source

Comparing the effect of intermittent diazepam and continuous phenobarbital in preventing recurrent febrile seizures among children under 6 years old: A systematic review and meta-analysis

Journal of Research in Medical Sciences, 2023
Background: Febrile convulsion (FC) is the most common and preventable seizure in children. This study aimed to assess the effectiveness of the diazepam and phenobarbital for preventing recurrent FC. Materials and Methods: In this systematic review study,
Leili Faraji Gavgani, Delara Laghousi, Parvin Sarbakhsh, Leila Jahangiri, Nafiseh Vahed, Sakineh Hajebrahimi   +5 more
doaj   +1 more source

Oral Loading of Phenobarbital to Achieve Therapeutic Effects in Pediatric Patients with Acute Repetitive Seizures [PDF]

Annals of Child Neurology, 2023
Purpose Intravenous phenobarbital has not been available at our institution since 2019. This study aimed to determine the effectiveness of oral phenobarbital loading at a dose of 15 to 20 mg/kg to achieve therapeutic serum levels and clinical seizure ...
Jemima Grace D. Fronda, Mel Michel G. Villaluz, Cristina M. Cruz-Urbi   +2 more
doaj   +1 more source

C45 - Hydrogels oraux pH-sensibles contenant du phénobarbital pour une utilisation potentielle en pédiatrie

Journal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction : Le but de l’étude était de développer des hydrogels oraux à base de chitosane pH- sensibles, capables de libérer le phénobarbital dans l'intestin grêle du nouveau-né.
Alphonse Rodrigue DJIBOUNE, Nicolas Anton, Sidy Mouhamed Dieng, Papa Mady Sy, Diouf Diouf, Gora Mbaye, Mamadou Soumboundou, Said Ennahar, Nadia Messaddeq, Thierry Vandamme, Mounibe Diarra   +10 more
doaj   +1 more source

Phenobarbital dyskinesia [PDF]

Postgraduate Medical Journal, 1978
Summary A patient was admitted to hospital following an overdose of phenobarbital. During her recovery she developed both chorea and torsion dystonia which could only be related to her high plasma phenobarbital levels.
openaire   +2 more sources

Measurement of Blood Phenobarbital Concentration in Newborns Admitted to The NICU of Imam Reza Hospital and Receiving The Drug Via Intravenous Mode [PDF]

Asia Pacific Journal of Medical Toxicology
Introduction: Newborns may be treated with phenobarbital for many reasons. Because in each region, depending on different races and genetic factors, different pharmacokinetic conditions govern the drug.
Hamidreza Goldouzi, Ashraf Mohammadzadeh, Ahmadshah Farhat, Anahita Alizadeh, F Yazdanpanah, Tina Loghmani, Ezzat Khodashenas   +6 more
doaj   +1 more source

Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats

Journal of Lipid Research, 1972
The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj   +1 more source