Results 21 to 30 of about 55,162 (292)
Journal of Feline Medicine and Surgery Open Reports, 2022 Case summary A female neutered domestic longhair cat, aged 1 year and 5 months, presented with lymphadenomegaly and anaemia following therapy with phenobarbital for idiopathic epilepsy.
Michelle Walton-Clark +2 more
doaj +1 more source
Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. [PDF]
, 2008 The liver is responsible for key metabolic functions, including control of normal homoeostasis in response to diet and xenobiotic metabolism/detoxification.
Finn, Robert +3 more
core +2 more sources
Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit
BMC Pediatrics, 2018 Background Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication.
Tamorah Lewis +2 more
doaj +1 more source
BMC Pharmacology and Toxicology, 2022 Background The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes.
Imran Mukhtar +5 more
doaj +1 more source
Acta Medica Iranica, 2022 Phenobarbital is still one of the drugs of choice in managing patients with brain injury in the intensive care unit (ICU). However, the impact of acute physiological changes on phenobarbital pharmacokinetic parameters is not well studied.
Seyedeh Sana Khezrnia +9 more
doaj +1 more source
Phenobarbital dyskinesia [PDF]
Postgraduate Medical Journal, 1978 Summary A patient was admitted to hospital following an overdose of phenobarbital. During her recovery she developed both chorea and torsion dystonia which could only be related to her high plasma phenobarbital levels.
openaire +2 more sources
Measurement of Blood Phenobarbital Concentration in Newborns Admitted to The NICU of Imam Reza Hospital and Receiving The Drug Via Intravenous Mode [PDF]
Asia Pacific Journal of Medical ToxicologyIntroduction: Newborns may be treated with phenobarbital for many reasons. Because in each region, depending on different races and genetic factors, different pharmacokinetic conditions govern the drug.
Hamidreza Goldouzi +6 more
doaj +1 more source
Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats
Journal of Lipid Research, 1972 The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj +1 more source
Standard Error of Empirical Bayes Estimate in NONMEM® VI. [PDF]
, 2012 The pharmacokinetics/pharmacodynamics analysis software NONMEM® output provides model parameter estimates and associated standard errors. However, the standard error of empirical Bayes estimates of inter-subject variability is not available. A simple and
Bae, Kyun-Seop +4 more
core +2 more sources
The Economic Costs of Malaria in Children in three Sub-Saharan Countries: Ghana, Tanzania and Kenya. [PDF]
, 2013 Malaria causes significant mortality and morbidity in sub-Saharan Africa (SSA), especially among children less than five years of age (U5 children).
Constenla, Dagna +4 more
core +2 more sources