Results 201 to 210 of about 63,407 (320)

Acute cyclosporine overdose in a child with nephrotic syndrome: a case report and literature review. [PDF]

Front Pediatr
Song ES, Yang EM.
europepmc   +1 more source

PRELID1 and VDAC3 Coordinate a Senescence‐Like State in Germinal Center B Cells to Promote IL‐7–Driven Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
Colorectal cancer is characterized by an immunosuppressive microenvironment that limits immunotherapy efficacy. We identify a senescence‐like state in germinal center B cells driven by the PRELID1–VDAC3 axis, which promotes IL‐7 secretion, alleviates CD8+ T‐cell exhaustion, and enhances antitumor immunity. Targeting this pathway improves responsiveness
Yuhan Liao, Huimeng Xu, Xinghua Zhuo, Shupeng Hu, Lanhui Huang, Zhe Hao, Jianxiong Chen, Yulu Wang, Jun Zhou   +8 more
wiley   +1 more source

Retrospective study on canine idiopathic epilepsy treatment in primary care practices in the United States. [PDF]

Front Vet Sci
Pompermaier E, Morrison JA, Stabile F, De Risio L.   +3 more
europepmc   +1 more source

Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins [PDF]

, 1987

openalex   +1 more source

Digoxin potentiates the anticonvulsant effect of low-dose phenobarbital and clonazepam under primary generalized seizures with different neurochemical mechanisms

, 2023
В. В. Цивунін, С. Ю. Штриголь   +1 more
openalex   +2 more sources

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Agreement between a point-of-care analyzer and a reference laboratory analyzer for plasma phenobarbital quantification in dogs and cats. [PDF]

Open Vet J
Scherf G, Van Caenegem N.
europepmc   +1 more source

Association of HLA genotypes with phenobarbital hypersensitivity in children [PDF]

, 2016
Wiparat Manuyakorn, Surakameth Mahasirimongkol, Plernpit Likkasittipan, Wasu Kamchaisatian, Sukanya Wattanapokayakit, Wimala Inunchot, Anannit Visudtibhan, Nuanjun Wichukchinda, Suwat Benjaponpitak   +8 more
openalex   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu, Mei Liu, Changxing Gao, Cheng Zhao, Feijie Zhao, Shuqing Dong, Bo Zhang, Qianmei Liu, Wenqian Zhang, Ming Zhao, Qianjin Lu   +10 more
wiley   +1 more source

Reply: Comparative Dose-Response of Diazepam, Lorazepam, and Phenobarbital for Alcohol Withdrawal in the Emergency Department. [PDF]

Ann Pharmacother
Lebin JA, Goldberg EM, Hawk KF, Burnham EL, Hoppe JA.   +4 more
europepmc   +1 more source