Results 211 to 220 of about 78,657 (383)

Syntheses of Phenobarbital Derivatives. II

open access: bronze, 1961
Zensaku Fujinaga   +2 more
openalex   +2 more sources

Biallelic pathogenic variants in COX11 are associated with an infantile‐onset mitochondrial encephalopathy

open access: yesHuman Mutation, Volume 43, Issue 12, Page 1970-1978, December 2022., 2022
Abstract Primary mitochondrial diseases are a group of genetically and clinically heterogeneous disorders resulting from oxidative phosphorylation (OXPHOS) defects. COX11 encodes a copper chaperone that participates in the assembly of complex IV and has not been previously linked to human disease. In a previous study, we identified that COX11 knockdown
Rocio Rius   +15 more
wiley   +1 more source

Gallstone Ileus in a 25-Year-Old Female With Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: A Case Report. [PDF]

open access: yesCase Rep Gastrointest Med
Onoda H   +7 more
europepmc   +1 more source

Design and Synthesis of 68Ga‐Labeled Peptide‐Based Heterodimers for Dual Targeting of NTS1 and GRPR

open access: yesChemMedChem, EarlyView.
Tumor heterogeneity is challenging for cancer diagnosis and treatment. This study designs and evaluates three gallium‐68 radiolabeled heterodimers targeting two G‐protein coupled receptors, namely NTS1 (neurotensin receptor 1) and GRPR (gastrin‐releasing‐peptide receptor). The branched analogue [68Ga]Ga‐JMV 7266 preserves NTS1 affinity, exhibits higher 
Sacha Bodin   +9 more
wiley   +1 more source

Survival outcomes of metastatic breast cancer patients by germline BRCA1/2 status in a large multicenter real‐world database

open access: yesInternational Journal of Cancer, Volume 152, Issue 5, Page 921-931, 1 March 2023., 2023
What's new? Despite the recent approval of novel therapeutics for germline BRCA1/2‐mutated metastatic breast cancer, data regarding outcomes and optimal treatment strategies are lacking. This study assessed the impact of germline BRCA mutations on metastatic breast cancer survival using data from a cohort of patients treated in an era predating PARP ...
Audrey Mailliez   +21 more
wiley   +1 more source

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