Results 231 to 240 of about 78,657 (383)

Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: Catalytic activity and other properties [PDF]

, 1974
Theodore A. van der Hoeven, David A. Haugen, Minor J. Coon   +2 more
openalex   +1 more source

Physiologically Based Pharmacokinetic Modeling to Predict Drug–Drug Interactions of Soticlestat as a Victim of CYP Induction and Inhibition, and as a Perpetrator of CYP and P–Glycoprotein Inhibition

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Soticlestat (TAK‐935) is a cholesterol 24‐hydroxylase inhibitor. A physiologically‐based pharmacokinetic model has been developed to predict potential soticlestat drug–drug interactions (DDIs) using the Simcyp v20 Population‐based Simulator and verified with data from single‐/multiple‐rising‐dose and clinical DDI studies.
Hongxia Jia, T. Eric Ballard, Liming Zhang, Lawrence Cohen, Mackenzie C. Bergagnini‐Kolev, Ian E. Templeton, Hannah M. Jones, Wei Yin   +7 more
wiley   +1 more source

Potential of Khaya senegalensis to mitigate epileptogenesis and cognitive dysfunction on kainate-induced post-status epilepticus model. [PDF]

IBRO Neurosci Rep
Kandeda AK, Foutse LY, Lewale S, Dimo T.
europepmc   +1 more source

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

, 1976
D A Haugen, Minor J. Coon
openalex   +1 more source

Dietary fiber chemical structure determined gut microbiota dynamics

iMeta, Volume 1, Issue 4, December 2022., 2022
The monosaccharide composition and glycosidic bond configuration determine the CAZyme that could hydrolyze it. Thus, bacteria encoding specific CAZyme utilize different structured dietary fibers. Compounded with bacterial interaction, gut microbiota dynamics is synergistically modulated.
Xin Meng, Jun Zheng, Fengqiao Wang, Jie Zheng, Dong Yang   +4 more
wiley   +1 more source

Efficacy of Levetiracetam vs Phenobarbital as First Line Therapy for the Treatment of Neonatal Seizures. [PDF]

J Pediatr Pharmacol Ther
Long D, Sutton C, Hale J.
europepmc   +1 more source

Interference by p-hydroxyphenobarbital in the 125I-radioimmunoassay of serum and urinary phenobarbital. [PDF]

, 1977
C.T. Viswanathan, Harold E. Booker, Peter G. Welling   +2 more
openalex   +1 more source

Squamate ventricular cardiomyocytes: Ploidy, proliferation, and heart muscle cell size in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Abstract Background While heart function is broadly conserved across vertebrates, the cellular phenotype of muscle cells (cardiomyocytes) varies across taxa and throughout ontogeny. Emerging evidence suggests that some attributes may correlate with the capacity for spontaneous cardiomyocyte replacement following injury.
Kathy Jacyniak, Karemna Barrera Jaimes, Minh Hanh Doan, Jordyn M. Chartrand, Matthew K. Vickaryous   +4 more
wiley   +1 more source

Investigating the Relationship Between Anti-seizure Medications and Bleeding Disorders: A Comprehensive Review of the Current Literature. [PDF]

Drugs Real World Outcomes
Mansoor A, Shahzad M, Zulfiqar E, Ahsan M, Adnan R, Shaeen SK, Banatwala UESS, Malikzai A.   +7 more
europepmc   +1 more source

Effect of Phenobarbital on Liver Functions in Patients with Dubin-Johnson Syndrome

, 1974
Mordechai Shani, Uri Seligsohn, Judith Ben-Ezzer   +2 more
openalex   +1 more source