Results 311 to 320 of about 86,047 (385)

Application of drug-induced sleep endoscopy in infants with dynamic upper airway collapse. [PDF]

Front Pediatr
Wei Q, Yang R, Chen X, Yi X, Liu J, Li Y.   +5 more
europepmc   +1 more source

The INSPECTOR study: enhanced feasibility for clinical translation of a multi‐cancer early detection method based on enzyme‐assisted high signal‐to‐noise ratio sequencing of methylated circulating tumor DNA

Cancer Communications, EarlyView.
Abstract Background Blood‐based cell‐free DNA (cfDNA) methylation testing has emerged as a promising approach for multi‐cancer early detection (MCED), holding the potential to improve cancer survival rates. However, traditional bisulfite‐based methods often encounter sensitivity limitations in detecting early‐stage malignancies or certain cancer types.
Hui‐Yan Luo, Wei Wei, Pansong Li, Qi‐Hua Zhang, Zhipeng Zhou, Liang Cui, Yong‐Bin Lin, Hong Yang, Xianyu Zhong, Qingfeng Liu, Han Yang, Kong‐Jia Luo, Hai‐Bo Qiu, Shu‐Qiang Yuan, Yuan‐Fang Li, Zhi‐Wei Zhou, Xiao‐Jun Lin, Bo‐Kang Cui, Rong‐Xin Zhang, Wen‐Hua Fan, He Huang, Chun‐Yan Lan, Jun‐Dong Li, Zhi‐Qiang Wang, Bin‐Kui Li, Rong‐Ping Guo, Jun Tang, Xin Huang, Mian Xi, Yuying Liu, Chuanbo Xie, Shi Chen, Zhi‐Hu Li, Yu‐Hua Liu, Xiao‐Ting Zhang, Qiang Zeng, Xin Yi, Rui‐Hua Xu   +37 more
wiley   +1 more source

Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling

Cell Biology International, EarlyView.
ABSTRACT Aggressiveness and resistance to treatments are significant problems in cancer management. In this scenario, searching for new pharmacological targets for therapies is essential. The APE1 redox domain coactivates transcription factors that favor cancer malignancy. One of APE1's targets, STAT3, coordinates the transcription of genes involved in
Mariana Moreno de Sousa Rodrigues, Priscyanne Barreto Siqueira, Ana Clara Cavallo Dobao, Maria Eduarda Barbosa Mourão, Bruno Ricardo Barreto Pires, Adenilson de Souza da Fonseca, Ísis Salviano Soares de Amorim, Andre Luiz Mencalha   +7 more
wiley   +1 more source

Coronary Ectasia and ST Elevation Myocardial Infarction Patients: Does Atherosclerosis Influence Periprocedural Management and Long‐Term Prognosis?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery ectasia (CAE) influences procedural outcomes in the context of ST‐elevation myocardial infarction (STEMI); however, its relationship with atherosclerotic coronary artery disease (ACAD) remains unclear. Aims This study aimed to compare clinical and procedural characteristics, as well as outcomes, in patients with ...
Victorine Fraichot, Jeanne Varlot, Florian Eggenspieler, Nassima Djaballah, Pierre Adrien Metzdorf, Edoardo Camenzind, Batric Popovic   +6 more
wiley   +1 more source

Gallstone Ileus in a 25-Year-Old Female With Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: A Case Report. [PDF]

Case Rep Gastrointest Med
Onoda H, Kuroda M, Takeguchi R, Tanaka R, Ishii D, Miyagi H, Hirasawa M, Takahashi S.   +7 more
europepmc   +1 more source

Intravascular Lithotripsy for Coral Reef Aorta and Chronic Mesenteric Ischemia: Case Report and Comprehensive Literature Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Chronic mesenteric ischemia (CMI) secondary to extensive paravisceral atherosclerosis is a rare but challenging vascular condition, often presenting with postprandial abdominal pain, weight loss, and claudication due to impaired blood flow. While surgical bypass is a standard treatment, it carries significant risks, particularly in patients ...
Dipankar Mukherjee, Bibhas Amatya, David J. Spinosa   +2 more
wiley   +1 more source

Comparative Analysis of Intravascular Lithotripsy With and Without Atherectomy in Severely Calcified Coronary Lesions Using OCT and OFDI

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular lithotripsy (IVL) fractures calcified plaques and facilitates lesion expansion; however, unlike atherectomy devices, it does not reduce calcium volume. The therapeutic efficacy and safety of combining IVL with atherectomy remain unclear. Therefore, this study aimed to evaluate, through optical coherence tomography (OCT)
Marohito Nakata, Masami Abe, Toshiya Chinen, Kentaro Nakamura   +3 more
wiley   +1 more source

Chitosan Nanoparticles for Topical Drug Delivery in Chemotherapy-Induced Alopecia: A Comparative Study of Five Repurposed Pharmacological Agents. [PDF]

Pharmaceuticals (Basel)
Fereig SA, Youshia J, El-Zaafarany GM, Arafa MG, Abdel-Mottaleb MMA.   +4 more
europepmc   +1 more source

VERMONT: Vessel Fractional Flow Reserve (vFFR) Assessment of Stenosis Severity: A Prospective Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Vessel fractional flow reserve (vFFR) is an angiogram‐based technique validated in early studies; however, data on its real‐time diagnostic performance and integration into routine workflow remain limited. Aims The VERMONT study evaluated the diagnostic accuracy and time efficiency of real‐time vFFR versus conventional wire‐based ...
Daniel Akrawi, Krishna Kadappu, James Xu, Tamer Yousef Naguib Badie, Oliver Gibbs, Hashim Kachwalla, Phong T. D. Nguyen, Rahul Kurup, Upul Premawardhana, Sidney Lo, Justyn Huang, Hao Tran, Kavie Soosapilla, Aiden O'Loughlin, Annemarie Hennessy, Giuseppe Femia   +15 more
wiley   +1 more source