Results 311 to 320 of about 1,201,228 (414)

The Encapsulation Strategies for Targeted Delivery of Probiotics in Preventing and Treating Colorectal Cancer: A Review

open access: yesAdvanced Science, EarlyView.
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong   +5 more
wiley   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

Hydrogel‐Transformable Probiotic Powder for Targeted Eradication of Helicobacter pylori with Enhanced Gastric Mucosal Repair and Microbiota Preservation

open access: yesAdvanced Science, EarlyView.
A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai   +9 more
wiley   +1 more source

Next-Gen Point-of-Care Tool for Ultra-Sensitive Detection of Urinary Spermine for Prostate Cancer Diagnosis. [PDF]

open access: yesACS Sens
Dehghani P   +6 more
europepmc   +1 more source

An Ultra‐Fast Rolling Double‐Helical Robot Driven by Constant Humidity

open access: yesAdvanced Science, EarlyView.
A double‐helical robot named Dualicalbot is proposed to achieve a high‐speed rolling under a constant humidity. The special asymmetric structural design makes sure that the two helices alternately drive the robot to roll with a remarkable speed of 5.8 BL s−1, 4.8 times faster than the fastest robot driven by a constant environment and surpassing the ...
Chuhan Xu   +5 more
wiley   +1 more source

An Intelligent and Conductive Hydrogel with Multiresponsive and ROS Scavenging Properties for Infection Prevention and Anti‐Inflammatory Treatment Assisted by Electrical Stimulation for Diabetic Wound

open access: yesAdvanced Science, EarlyView.
This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang   +4 more
wiley   +1 more source

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