Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Rapid removal of phenol from aqueous solutions by AC_Fe3O4 nano-composite: Kinetics and equilibrium studies [PDF]
Background and purpose: Phenol and its derivatives are used as raw material in many chemical, pharmaceutical and petrochemical industries. It is classified as priority pollutant, due to its high toxicity. In this study, the magnetic activated carbon nano-
Esrafili dizaji, A. +3 more
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Exploring the prevalence and risks of eating disorders in Lebanon’s athletic community
The intersection of eating disorders and competitive sports presents a critical issue that demands attention. Athletes, driven by the desire for peak performance and often subjected to intense physical and psychological pressures, are particularly ...
Zahra Sadek +6 more
doaj +1 more source
Characterization and bioactive potential of epicuticular wax from date fruits [PDF]
Date fruits (DFs) are lucrative fruits with both nutritional and medicinal benefits. Although DF byproducts have gained interest as potential functional food ingredients, the functional role of DF waxes remains unexplored.
Bhawna Sobti +4 more
doaj +3 more sources
Initiation of polymerization by tetrabutylammonium p-lithophenoxide p-lithiophenoxide [PDF]
Compound is an efficient initiator capable of producing a polymer with a phenol group at the initiating end of the chain. Derivative may be used as a polymerization initiator to produce large quantities of phenol-terminated ...
Hirshfield, S. M.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Lebanon is undergoing a nutrition transition that increases the risk of nutritional deficiencies and noncommunicable diseases. This study assessed diet quality—measured by adherence to the Mediterranean diet (MD), household dietary diversity (HDD), and ...
Myriam Abboud +4 more
doaj +1 more source
Advanced Fenton processing of aqueous phenol solutions:a continuous system study including sonication effects [PDF]
Our previous report based on a batch reactor system for the Advanced Fenton Process (AFP) showed that pH, hydrogen peroxide and the organic substances treated are among the most important factors affecting the oxidation efficiency.
Bremner, D. H. +3 more
core +3 more sources
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

