Results 41 to 50 of about 1,664,619 (266)

Molecular simulation of liquid-liquid extraction of acetic acid and acetone from water in the presence of nanoparticles based on prediction of solubility parameters

open access: yesHeliyon
In this work, molecular dynamics simulation (MD) was used for studying the liquid-liquid extraction of acetic acid and acetone from water in the presence of nanoparticles.
Hojatollah Moradi   +2 more
doaj   +1 more source

The phenomenon of fear in the collection 'Princ Vatre' from Filip David and 'Sara i Serafina' from Dževad Karahasan [PDF]

open access: yesUniverzitetska Misao, 2020
In literary works, fear appears as a phenomenon frequently because fear is something that humans face from the beginning of their lives. This paper strives to examine the source, characterization, the outcome of this phenomenon in the works "Princ Vatre"
Beširović Nejira
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Artificial intelligence and creation of complex organizational and technical systems (Part 1)

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки, 2022
Background. Complex organizational and technical systems with elements of artificial intelligence are considered, that is, systems, in the course of their functioning, unconventional tasks related to human creative abilities are solved.
M.Yu. Babich
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

On the Phenomenon of Autocomputability

open access: yesElectronic Notes in Theoretical Computer Science, 2000
Following Trakhtenbrot's concept of autoreducible set, we look at the general phenomenon of autocomputability of infinite binary sequences. We define another appropriate mathematical model of this concept: the strongly autoreducible set. For this purpose, we need to introduce a natural restricted form of wtt-reduction between sets: minimal weak truth ...
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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