Results 11 to 20 of about 30,805 (301)

Development of Phenothiazine Hybrids with Potential Medicinal Interest: A Review

Molecules, 2022
The molecular hybridization approach has been used to develop compounds with improved efficacy by combining two or more pharmacophores of bioactive scaffolds.
Marina C. Posso, Fernanda C. Domingues, Susana Ferreira, Samuel Silvestre   +3 more
doaj   +2 more sources

Antioxidant Properties of New Phenothiazine Derivatives

Antioxidants, 2022
Phenothiazine and its derivatives have a number of properties that contribute to their wider practical use in the production of biologically active substances, drugs, dyes, etc.
Olesya Voronova, Sergey Zhuravkov, Elena Korotkova, Anton Artamonov, Evgenii Plotnikov   +4 more
doaj   +2 more sources

Synthesis of Novel Chalcone-Based Phenothiazine Derivatives as Antioxidant and Anticancer Agents

Molecules, 2020
Based on reported results for the potential medicinal impact of phenothiazine core, as well as the chalcone skeleton that is widely present in many natural products, together with their reported bioactivities, the present work was aimed at combining both
Nourah A. Al Zahrani, Reda M. El-Shishtawy, Mahmoud M. Elaasser, Abdullah M. Asiri   +3 more
doaj   +2 more sources

Exploring Micelles and Nanospheres as Delivery Systems for Phenothiazine Derivatives in Cancer Therapy [PDF]

Pharmaceutics
Objectives: Cancer remains one of the leading causes of death worldwide, and thus, there is a need for the development of innovative and more effective treatment strategies.
Katarzyna Jelonek, Monika Musiał-Kulik, Małgorzata Pastusiak, Aleksander Foryś, Andrzej Zięba, Janusz Kasperczyk   +5 more
doaj   +2 more sources

Electrochemical generation of phenothiazin-5-ium. A sustainable strategy for the synthesis of new bis(phenylsulfonyl)-10H-phenothiazine derivatives [PDF]

Scientific Reports
In this work, the electrochemical generation of phenothiazin-5-ium (PTZox) from the direct oxidation of phenothiazine (PTZ) in a water/acetonitrile mixture using a commercial carbon anode and conventional stainless steel cathode is reported.
Niloofar Mohamadighader, Faezeh Zivari-Moshfegh, Davood Nematollahi   +2 more
doaj   +2 more sources

Ultraviolet radiation thin film dosimetry: A review of properties and applications [PDF]

Photochemistry and Photobiology, Volume 101, Issue 3, Page 532-545, May/June 2025.
Solar ultraviolet (UVR) exposure measurements at various body sites during daily activities, as well as on plants, animals, and any field sites of interest are essential for an understanding of the UVR environment. Thin film dosimetry provides a practical and versatile method for conducting these measurements.
Alfio V. Parisi, Nathan J. Downs, Peter Schouten, Damien P. Igoe, Joanna Turner, Abdurazaq Amar, Lisa Wainwright, Adrian Dawes, Harry Butler, Stijn Dekeyser   +9 more
wiley   +2 more sources

10-[(4-Nitrophenyl)ethynyl]-10H-phenothiazine

IUCrData, 2022
The title compound, C20H12N2OS, is a 10-ethynyl-10H-phenothiazine derivative. The phenothiazine unit has a butterfly shape, where the folding angle between the two benzene rings is 153.87 (7)°, which is almost as in other reported phenothiazine ...
Tsunehisa Okuno, Ikue Doi
doaj   +1 more source

The Effect of Molecular Conformations and Simulated "Self-Doping" in Phenothiazine Derivatives on Room-Temperature Phosphorescence.

Angewandte Chemie, 2022
The research of purely organic room-temperature phosphorescence (RTP) materials has drawn great attention for their wide potential applications. Besides single-component and host-guest doping systems, the self-doping with same molecule but different ...
Mingxue Gao, Yunfeng Tian, Xiaoning Li, Yanxiang Gong, Manman Fang, Jie Yang, Zhuguo Li   +6 more
semanticscholar   +1 more source

Tuning the Fluorescence and the Intramolecular Charge Transfer of Phenothiazine Dipolar and Quadrupolar Derivatives by Oxygen Functionalization

Journal of the American Chemical Society, 2021
A series of new naphthalimide and phenothiazine-based push–pull systems (NPI-PTZ1–5), in which we structurally modulate the oxidation state of the sulfur atom in the thiazine ring, i.e., S(II), S(IV), and S(VI), was designed and synthesized by the Pd ...
Yogajivan Rout, C. Montanari, Erika Pasciucco, R. Misra, B. Carlotti   +4 more
semanticscholar   +1 more source

Pleiotropic actions of phenothiazine drugs are detrimental to Gram-negative bacterial persister cells

Communications Biology, 2022
Bacterial persister cells are temporarily tolerant to bactericidal antibiotics but are not necessarily dormant and may exhibit physiological activities leading to cell damage. Based on the link between fluoroquinolone-mediated SOS responses and persister
S. G. Mohiuddin, Thao Vy Nguyen, Mehmet A. Orman   +2 more
semanticscholar   +1 more source