Results 51 to 60 of about 9,460 (190)

Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

open access: yesBiomolecules, 2016
There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities.
Shiying Wu   +2 more
doaj   +1 more source

Research progress in photo‐controlled radical involved luminescence materials

open access: yesFlexMat, EarlyView.
This review systematically dissects radical generation mechanisms, triplet‐exciton photophysics, material design strategies, and cutting‐edge applications in smart encryption, environmental sensing, and 3D printing. Abstract In recent years, photo‐controlled radical room‐temperature phosphorescent (RTP) materials have shown significant application ...
Sichen Meng   +8 more
wiley   +1 more source

Ruthenium‐Catalyzed Nitrile‐Acrylate Reductive Coupling by 2‐Propanol: Synthesis of Enantioenriched β‐Amino Esters

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
The first nitrile reductive couplings beyond stoichiometric metals or metalloids are described. Using a ruthenium catalyst derived from RuHCl(CO)(PPh3)3 and Cy‐BIPHEP, 2‐propanol‐mediated reductive coupling of phenyl acrylate with aromatic or aliphatic nitriles delivers α,β‐unsaturated β‐amino esters.
Sebastian Höthker   +3 more
wiley   +2 more sources

The Large Action of Chlorpromazine: Translational and Transdisciplinary Considerations in the Face of COVID-19

open access: yesFrontiers in Pharmacology, 2020
Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome (SARS) in humans that is caused by SARS-associated coronavirus type 2 (SARS-CoV-2).
Emmanuel Stip   +12 more
doaj   +1 more source

Photogenerated fluphenazine radical cations for antiviral functionalization of polypropylene masks

open access: yesPolymer International, EarlyView.
Fluphenazine impregnated into nonwoven polypropylene masks is photoexcited to a radical cation, which inactivates viruses on the polymer surface without causing damage to the masks. Abstract The incorporation of photoactive molecules into polymeric substrates offers a compelling route to introduce advanced functionality while preserving the host ...
Lilian Martins‐Nascimento   +4 more
wiley   +1 more source

Revisiting small‐molecule fluorescent probes in food freshness detection

open access: yesSmart Molecules, EarlyView.
Fluorescent probes serve as versatile tools for food freshness monitoring. This review summarizes recent advances in probes targeting biogenic amines, hydrogen sulfide, pH values, and other key spoilage markers, highlighting their design principles, sensing mechanisms, and practical applications in food quality monitoring. Abstract Food spoilage driven
Xinrui Wang   +5 more
wiley   +1 more source

A photoimmune synergizing RNA interference technology for highly effective antitumor treatment

open access: yesSmart Molecules, EarlyView.
We developed a red‐light‐activated small‐molecule photosensitizer FNBS, which enables simultaneous photodynamic immunotherapy and RNA interference. FNBS can induce pyroptosis, immunogenic cell death and RNA degradation, avoiding the carrier‐dependent delivery drawbacks of conventional RNAi therapy, converting cold tumors into hot tumors and ...
Xiang Xia   +6 more
wiley   +1 more source

Modified Methods for the Synthesis of Carbazole from Phenothiazine

open access: yesMolecules, 2001
Lithium, used in conjunction with triphenylphosphine or sodium metal, produces a high yield of carbazole when reacted with phenothiazine.
Steven C. Farmer, R. Bryan Miller
doaj   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

open access: yesPhotochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi   +2 more
wiley   +1 more source

Dissolution Thermodynamics and Preferential Solvation of Phenothiazine in Some Aqueous Cosolvent Systems

open access: yesLiquids
Published equilibrium mole fraction solubilities of phenothiazine in ethanol, propylene glycol and water as mono-solvents at several temperatures were investigated to find standard apparent thermodynamic quantities of dissolution mixing and solvation ...
Fleming Martínez   +2 more
doaj   +1 more source

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