Results 251 to 260 of about 29,628 (301)
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Journal of Medicinal Chemistry, 2011
A total of 53 N-benzoylated phenoxazines and phenothiazines, including their S-oxidized analogues, were synthesized and evaluated for antiproliferative activity, interaction with tubulin, and cell cycle effects.
H. Prinz +9 more
semanticscholar +1 more source
A total of 53 N-benzoylated phenoxazines and phenothiazines, including their S-oxidized analogues, were synthesized and evaluated for antiproliferative activity, interaction with tubulin, and cell cycle effects.
H. Prinz +9 more
semanticscholar +1 more source
Antitumor Properties of Phenothiazines
Cancer Investigation, 1991The purpose of this review is to describe and evaluate the antineoplastic properties of phenothiazines. The present research studies suggest that many phenothiazines do not show significant antitumor and antineoplastic activity and so they cannot be used as potential drugs to treat cancer. However some of their derivatives help indirectly in decreasing
Sitaraghav R. Gollapudi +3 more
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Journal of Mental Science, 1958
7044 is a new phenothiazine derivative which can be regarded, pharmacologically, as resembling chlorpromazine much more closely than it does promethazine. It is said to have the characteristic central properties of chlorptomazine more highly developed, and in addition anti-adrenaline properties with anti-histamine properties comparable to those of ...
A. A. Baker, J. G. Thorpe
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7044 is a new phenothiazine derivative which can be regarded, pharmacologically, as resembling chlorpromazine much more closely than it does promethazine. It is said to have the characteristic central properties of chlorptomazine more highly developed, and in addition anti-adrenaline properties with anti-histamine properties comparable to those of ...
A. A. Baker, J. G. Thorpe
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Direct modification of bioactive phenothiazines by exposure to laser radiation.
Recent Patents on Anti-Infective Drug Discovery, 2011Whereas exposure of combinations of a phenothiazine and bacterium to incoherent UV increases the activity of the phenothiazine, exposure of the phenothiazine alone does not yield an increase of its activity.
M. Pascu +12 more
semanticscholar +1 more source
The Long-Acting Phenothiazines
Archives of General Psychiatry, 1975Injected intramuscularly, the enanthane and decanoate esters of the phenothiazine fluphenazine are an effective treatment of the disordered behavior and thinking of schizophrenia. The decanoate preparation is not only slightly longer-acting but also has a smaller incidence of side-effects that the enanthate.
James E. Groves, Michel R. Mandel
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Chemistry - An Asian Journal, 2010
Triethoxysilyl functionalized phenothiazinyl ureas were synthesized and immobilized by in situ synthesis into mesoporous hybrid materials. The designed precursor molecules influence the structure of the final materials and the intermolecular distance of ...
Zhou Zhou +10 more
semanticscholar +1 more source
Triethoxysilyl functionalized phenothiazinyl ureas were synthesized and immobilized by in situ synthesis into mesoporous hybrid materials. The designed precursor molecules influence the structure of the final materials and the intermolecular distance of ...
Zhou Zhou +10 more
semanticscholar +1 more source
Sensitivity to a Phenothiazine (Butaperazine)
Canadian Psychiatric Association Journal, 1968A second study of butaperazine on twenty-two patients compared to a previous group of twenty-four patients revealed rather similar results. Twenty of the subjects were involved in both studies, with an eleven-week period off medication in between the two treatment regimes.
Laska E, Simpson Gm
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, 2010
Thiolated phenylethynyl phenothiazines can be regarded as redox-active “alligator clips”. They are readily synthesized from ethynyl phenothiazines and show intense blue-green luminescence upon ultraviolet (UV) excitation.
C. Barkschat +3 more
semanticscholar +1 more source
Thiolated phenylethynyl phenothiazines can be regarded as redox-active “alligator clips”. They are readily synthesized from ethynyl phenothiazines and show intense blue-green luminescence upon ultraviolet (UV) excitation.
C. Barkschat +3 more
semanticscholar +1 more source
Phenothiazine: The Parent Molecule
Current Drug Targets, 2006Phenothiazine is an aromatic tricyclic compound that first emerged from the furtive chemical activity surrounding the aniline dye industry at the latter half of the 19th century. It contains both nitrogen and sulphur atoms and is the parent molecule of a multitude of drugs that have enjoyed varied and extensive use throughout medical and veterinary ...
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