Results 41 to 50 of about 29,628 (301)

Antifungal Phenothiazines: Optimization, Characterization of Mechanism, and Modulation of Neuroreceptor Activity.

open access: yesACS Infectious Diseases, 2017
New classes of antifungal drugs are an urgent unmet clinical need. One approach to the challenge of developing new antifungal drugs is to optimize the antifungal properties of currently used drugs with favorable pharmacologic properties, so-called drug ...
Marhiah C. Montoya   +4 more
semanticscholar   +1 more source

Donor‐π‐Acceptor Photoinitiators for High‐Efficiency Visible LED and Sunlight Polymerization and High‐Precision 3D Printing

open access: yesAngewandte Chemie, EarlyView.
The proposed D‐π‐A structured dyes enable efficient electron transfer with additives, thanks to their tailored architecture, making them ideal for high‐performance photoinitiating systems. They allow the fabrication of high‐precision 3D printed objects and exhibit outstanding performance under sunlight.
Ji Feng   +9 more
wiley   +2 more sources

Trypanosoma cruzi: effect of phenothiazines on the parasite and its interaction with host cells

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Phenothiazines were observed to have a direct effect on Trypanosoma cruzi and on its in vitro interaction with host cells. They caused lysis of trypomastigotes (50 uM/24 h) and,to a lesser extent, epimastigote proliferation.
Solange L. de Castro   +2 more
doaj   +1 more source

Photoredox Catalysts Based on N‐(Hexyl)benzothioxanthene‐3,4‐dicarboximide for Photopolymerization and 3D Printing Under Visible Light

open access: yesAngewandte Chemie, EarlyView.
In this work, two benzothioxanthene imide dyes demonstrate excellent photochemical properties. When used as photocatalysts, they work with amine and iodonium salt or sulfonium salt to form different three‐component systems for effectively initiating photopolymerization under visible light, through photoredox catalysis processes.
Bin Song   +10 more
wiley   +2 more sources

Amplified Sensitivity in SERS Detection of L1CAM With Silver Plasmonic Mesoporous Silica Capsules on an Imprinted Films

open access: yesAdvanced Materials Interfaces, EarlyView.
This study presents core‐shell Au‐Ag NPs and a novel molecularly imprinted polymer (MIP)‐based material targeting L1CAM. Thionine is used as a monomer to create the MIP on a carbon screen‐printed electrode. Functionalized Au‐AgNCs with Raman reporter 4‐mercaptobenzoic acid and anti‐L1CAM enable selective detection via surface‐enhanced Raman scattering ...
Yuselis Castaño‐Guerrero   +6 more
wiley   +1 more source

Organophotoredox‐Catalyzed Postfunctionalization of Poly(methacrylate) Derivatives via Radical–Polar Crossover Phosphonylation

open access: yesAngewandte Chemie, EarlyView.
The organophotoredox‐catalyzed postfunctionalization of polymers with a redox‐active moiety using trialkyl phosphite nucleophiles afforded the corresponding phosphonate‐containing polymers via the radical–polar crossover process, in which a carbocation equivalent is generated to react with nucleophiles.
Tomohiro Tamano   +3 more
wiley   +2 more sources

A Double-Edged Sword: Thioxanthenes Act on Both the Mind and the Microbiome

open access: yesMolecules, 2021
The rising tide of antibacterial drug resistance has given rise to the virtual elimination of numerous erstwhile antibiotics, intensifying the urgent demand for novel agents. A number of drugs have been found to possess potent antimicrobial action during
Marianne Ø. Poulsen   +5 more
doaj   +1 more source

Electrocrystallization of Phenothiazine [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1987
Abstract New cation radical salts of phenothiazine with (1:1), (3:2), and (2:1) compositions were prepared by the method of electrochemical oxidation. The electrical resistivities measured on the compaction of crystalline powder were 103–105 Ω cm at room temperature in the case of the complex salts.
Michiko Yoshitake   +2 more
openaire   +2 more sources

Bioorthogonal Reaction of o‐Quinone with Furan‐2(3H)‐One for Site‐Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes

open access: yesAdvanced Science, EarlyView.
A site‐selective, efficient, and mild tyrosine conjugation via tyrosinase oxidation and nucleophilic addition, allowing for site‐selective functionalization of peptides, recombinant proteins, and IgGs. Site‐selective mono‐functionalization of IgGs at Y296 enables the construction of immunoliposomes.
Hongfei Chen   +13 more
wiley   +1 more source

Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives

open access: yesBiomolecules, 2016
There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities.
Shiying Wu   +2 more
doaj   +1 more source

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