Results 41 to 50 of about 22,216 (274)
Advanced Energy and Sustainability Research, EarlyView.Organic electrode materials typically suffer from low electronic conductivity, requiring large amounts of carbon additives. Herein, a conducting polymer, PEDOT:PSS, is introduced as a partial replacement for carbon black, reducing the carbon content to 15 wt%.
Sathiya Priya Panjalingam +4 more
wiley +1 more source
Communications Biology, 2022 Phenothiazines, which have previously been approved as antipsychotic drugs, can also reduce growth and metabolism in a range of Gram-negative bacterial pathogens.
Sayed Golam Mohiuddin +2 more
doaj +1 more source
A Double-Edged Sword: Thioxanthenes Act on Both the Mind and the Microbiome
Molecules, 2021 The rising tide of antibacterial drug resistance has given rise to the virtual elimination of numerous erstwhile antibiotics, intensifying the urgent demand for novel agents. A number of drugs have been found to possess potent antimicrobial action during
Marianne Ø. Poulsen +5 more
doaj +1 more source
Aisha Bano - The Role of KCNQ (Kv7) Potassium Channels in Schizophrenia Deficits [PDF]
, 2013 For years, studies have been conducted to treat the positive and negative symptoms and cognitive deficits of schizophrenia; it has allowed to treat the positive symptoms through regulation of dopaminergic neurons and dopamine pathways; however, we still ...
Bano, Aisha
core +1 more source
New Roads Leading to Old Destinations: Efflux Pumps as Targets to Reverse Multidrug Resistance in Bacteria [PDF]
, 2017 Multidrug resistance (MDR) has appeared in response to selective pressures resulting from the incorrect use of antibiotics and other antimicrobials.
Amaral, Leonard +3 more
core +2 more sources
Trypanosoma cruzi: effect of phenothiazines on the parasite and its interaction with host cells
Memorias do Instituto Oswaldo Cruz, 1992 Phenothiazines were observed to have a direct effect on Trypanosoma cruzi and on its in vitro interaction with host cells. They caused lysis of trypomastigotes (50 uM/24 h) and,to a lesser extent, epimastigote proliferation.
Solange L. de Castro +2 more
doaj +1 more source
Mechanochromic Organic Materials: Molecular Mechanisms and Multidimensional Applications
Advanced Physics Research, EarlyView.Mechanochromic (MC) organic materials change color in response to mechanical force. This review elucidates the molecular mechanisms (e.g., aggregation‐induced emission, AIE) and explores their multidimensional applications in sensors, anti‐counterfeiting, biomedical devices, and structural health monitoring, providing a roadmap for future smart ...
Xiaozhe Yin +5 more
wiley +1 more source
Animal Research and One Health, EarlyView.The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao +12 more
wiley +1 more source
Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines
Revista de Ciências Farmacêuticas Básica e Aplicada, 2005 Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage to mitochondria, leading to the impairment of metabolic functions and apoptosis.
T. Rodrigues +4 more
doaj
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 10H-1,9-diazaphenothiazine was obtained in the sulphurisation reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted derivatives, containing alkyl and dialkylaminoalkyl groups at the thiazine nitrogen atom.
Beata Morak-Młodawska +8 more
doaj +1 more source