Results 21 to 30 of about 7,034 (195)

Docking and Biological Screening of Bezo[A]phenothiazinones as Novel Inhibitors of Bacterial Peptidogloycan Transpeptidase [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2019
Rising cases of antibiotic-resistant bacteria is a public health concern. Many approved antibiotics target penicillin-binding proteins example peptidoglycan transpeptidase (PTPase). Due to wide pharmacological activity of phenothiazines, new styryl, aryl,
Akachukwu E. Ibezim, Efeturi Onoabedje A., Kovo G. Akpomie   +2 more
doaj  

Analytical Applications of Reactions of Iron(III) and Hexacyanoferrate(III) with 2,10-Disubstituted Phenothiazines

International Journal of Analytical Chemistry, 2009
The presented review is devoted to analytical applications of reactions of Fe(III) and K3[Fe(CN)6] with 2,10-disubstituted phenothiazines (PT). It was found that iron(III) and hexacyanoferrate(III) ions in acidic media easily oxidized PT with the ...
Helena Puzanowska-Tarasiewicz, Joanna Karpińska, Ludmiła Kuźmicka   +2 more
doaj   +1 more source

Fluorene‐Framework Engineering Enables Narrowband Red Multi‐Resonance Emitters for High‐Efficiency With Negligible Roll‐Off Toward BT.2020

Angewandte Chemie, EarlyView.
σ‐Decoupled C9 fluorene‐framework topology control enables narrowband red MR emitters. SF‐BNO and PF‐BNO share the same BNO core, but differ in closed/open fluorene ring closure. SF‐BNO improves steric shielding and stability, while PF‐BNO enhances PLQY, orientation, and efficiency. Ex‐PSF and TE‐OLED architectures deliver ultra‐low efficiency roll‐off
Aradhya Rajput, Nisha Vergineya S, Subramanian Muruganantham, Meghana Tirupati, Odugu Pavan Kumar, Jun‐Yun Kim, Mi Young Chae, Jang Hyuk Kwon   +7 more
wiley   +2 more sources

Synthesis, electronic properties and self-assembly on Au{111} of thiolated (oligo)phenothiazines

Beilstein Journal of Organic Chemistry, 2010
(Oligo)phenothiazinyl thioacetates, synthesized by a one-pot sequence, are electrochemically oxidizable and highly fluorescent. SAMs can be readily formed from thiols prepared by in situ deprotection of the thioacetates in the presence of a gold-coated ...
Adam W. Franz, Svetlana Stoycheva, Michael Himmelhaus, Thomas J. J. Müller   +3 more
doaj   +1 more source

Phenothiazine-Related Critical Conditions: a Mini-Review

Общая реаниматология
Objective. The aim of this review is to summarize the pathological mechanisms associated with the toxicity of phenothiazines in overdose.Materials and methods.
D. E. Shumeyko
doaj   +1 more source

Optimization of Capillary Electrophoresis Separation Conditions ofChlorpromazine, Promethazineand Their Main Metabolitesby RSM

International Journal of Electrochemical Science, 2021
It is difficult to separate multiple phenothiazines with similar structures by capillary electrophoresis. However, under the experimental conditions optimized by response surface methodology (RSM), ten similar molecules of chlorpromazine, promethazine ...
Chungeng Li, Yanling Cheng, Kaowen Zhou
doaj   +1 more source

Type IV Pilus-Mediated Inhibition of Acinetobacter baumannii Biofilm Formation by Phenothiazine Compounds

Microbiology Spectrum, 2023
Infections by pathogenic Acinetobacter species represent a significant burden on the health care system, despite their relative rarity, due to the difficulty of treating infections through oral antibiotics.
Nam Vo, Benjamin S. Sidner, Yafan Yu, Kurt H. Piepenbrink   +3 more
doaj   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Trypanosoma cruzi: effect of phenothiazines on the parasite and its interaction with host cells

Memorias do Instituto Oswaldo Cruz, 1992
Phenothiazines were observed to have a direct effect on Trypanosoma cruzi and on its in vitro interaction with host cells. They caused lysis of trypomastigotes (50 uM/24 h) and,to a lesser extent, epimastigote proliferation.
Solange L. de Castro, Maria Nazaré C. Soeiro, Maria de Nazareth Leal de Meirelles   +2 more
doaj   +1 more source

Precisely Regulating 2.45 s Pure Blue Room‐Temperature Phosphorescence via Supramolecular Coordination

Advanced Science, EarlyView.
Herein, a pure deep blue room‐temperature phosphorescence (415 nm) with lifetime up to 2.45 s is successfully achieved by a covalently crosslinking purely organic material based on boric acid (BA) and 3,5‐dicarboxyphenylboronic acid (BOP) through a simple dehydration reaction, which can be adjusted precisely by supramolecular coordination with ...
Jun Wang, Xingting Que, Zhiming Chen, Jingsheng Zhang, Wei‐Lei Zhou, Wen‐Wen Xu   +5 more
wiley   +1 more source