Results 41 to 50 of about 7,034 (195)
Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian chloroquine-resistant fresh isolates of Plasmodium falciparum.
Carla MS Menezes +6 more
doaj +1 more source
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
A library of 21 tetrakis(phenothiazinyl)‐substituted silanes with broadly variable substituent decoration, which are fully reversible multistage redox systems with intense tunable emission from deep blue to yellow–green (441–533 nm), was rapidly synthesized by bromine–lithium exchange/borylation–Suzuki coupling of tetrakis(4‐bromophenyl)silane or by ...
Thomas P. M. Merke +4 more
wiley +1 more source
<b> Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines </b>
<p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: normal; text-align: justify; mso-layout-grid-align: none;"> Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage ...
T. RODRIGUES +4 more
doaj
Three methylpyridine‐functionalized TEMPOs were synthesized through an electron‐rich regulation strategy. The calculation of transition states supported the highest reaction efficiency of para‐MePy‐TEMPOs, which outperformed its analogues to have the best performance of AORFBs, opening a new avenue for exploring TEMPO‐based catholytes.
Shaopeng Wang +10 more
wiley +1 more source
Synthesis, Anticancer Activity, and Apoptosis Induction of Novel 3,6-Diazaphenothiazines
New 10-substituted derivatives of 3,6-diazaphenothiazine, containing the triple bond linker terminated with tertiary cyclic and acyclic amine groups, were synthesized and screened for their anticancer action.
Beata Morak-Młodawska +4 more
doaj +1 more source
Helical Dinaphthothiophenes Reveal the Limits of BN‐Based Optical Tuning
A BN‐7‐thia[5]helicene and an analogous CC‐7‐thia[5]helicene were prepared in two efficient synthetic routes. Their geometrical structures barely differ, which allows us to judge the influence of the BN substitution on the electronic properties. The formal substitution of carbon–carbon (CC) units by boron–nitrogen (BN) units is an established strategy ...
Yannik Appiarius +7 more
wiley +1 more source
Inhibition of Bacterial RNase P RNA by Phenothiazine Derivatives
There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities.
Shiying Wu +2 more
doaj +1 more source
The status quo for combating uprising antibacterial resistance is to employ synergistic combinations of antibiotics. Nevertheless, the currently available combination therapies are fast becoming untenable.
Maytham Hussein +9 more
doaj +1 more source
Research progress in photo‐controlled radical involved luminescence materials
This review systematically dissects radical generation mechanisms, triplet‐exciton photophysics, material design strategies, and cutting‐edge applications in smart encryption, environmental sensing, and 3D printing. Abstract In recent years, photo‐controlled radical room‐temperature phosphorescent (RTP) materials have shown significant application ...
Sichen Meng +8 more
wiley +1 more source

