Results 41 to 50 of about 6,613 (146)

10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
10H-1,9-diazaphenothiazine was obtained in the sulphurisation reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted derivatives, containing alkyl and dialkylaminoalkyl groups at the thiazine nitrogen atom.
Beata Morak-Młodawska, Krystian Pluta, Małgorzata Latocha, Małgorzata Jeleń, Dariusz Kuśmierz, Kinga Suwińska, Aleksander Shkurenko, Zenon Czuba, Magdalena Jurzak   +8 more
doaj   +1 more source

Smart Exploration of Perovskite Photovoltaics: From AI Driven Discovery to Autonomous Laboratories

Advanced Energy Materials, EarlyView.
In this review, we summarize the fundamentals of AI in automated materials science, and review AI applications in perovskite solar cells. Then, we sum up recent progress in AI‐guided manufacturing optimization, and highlight AI‐driven high‐throughput and autonomous laboratories.
Wenning Chen, Zheyu Zhang, Kelvian T. Mularso, Bonghyun Jo, Hyun Suk Jung   +4 more
wiley   +1 more source

Thiophene-forming one-pot synthesis of three thienyl-bridged oligophenothiazines and their electronic properties

Beilstein Journal of Organic Chemistry, 2016
The pseudo five-component Sonogashira–Glaser cyclization synthesis of symmetrically 2,5-diaryl-substituted thiophenes is excellently suited to access thienyl-bridged oligophenothiazines in a one-pot fashion. Three thienyl-bridged systems were intensively
Dominik Urselmann, Konstantin Deilhof, Bernhard Mayer, Thomas J. J. Müller   +3 more
doaj   +1 more source

Phenothiazines Inhibit SARS-CoV-2 Entry through Targeting Spike Protein

Viruses, 2023
Novel coronavirus disease 2019 (COVID-19), a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought an unprecedented public health crisis and continues to threaten humanity due to the persistent emergence ...
Taizhen Liang, Shiqi Xiao, Ziyao Wu, Xi Lv, Sen Liu, Meilin Hu, Guojie Li, Peiwen Li, Xiancai Ma   +8 more
doaj   +1 more source

An Insight Into the Potentiation Effect of Potassium Iodide on aPDT Efficacy

Frontiers in Microbiology, 2018
Antimicrobial photodynamic therapy (aPDT) is gaining a special importance as an effective approach against multidrug-resistant strains responsible of fatal infections. The addition of potassium iodide (KI), a non-toxic salt, is recognized to increase the
Cátia Vieira, Ana T. P. C. Gomes, Mariana Q. Mesquita, Nuno M. M. Moura, M. Graça P. M. S. Neves, M. Amparo F. Faustino, Adelaide Almeida   +6 more
doaj   +1 more source

<b> Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines </b>

Revista de Ciências Farmacêuticas Básica e Aplicada, 2009
<p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: normal; text-align: justify; mso-layout-grid-align: none;"> Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage ...
T. RODRIGUES, P. A.F. FARIA, F. S. PESSOTO, C. G. SANTOS, I. L. NANTES   +4 more
doaj  

Research progress in photo‐controlled radical involved luminescence materials

FlexMat, EarlyView.
This review systematically dissects radical generation mechanisms, triplet‐exciton photophysics, material design strategies, and cutting‐edge applications in smart encryption, environmental sensing, and 3D printing. Abstract In recent years, photo‐controlled radical room‐temperature phosphorescent (RTP) materials have shown significant application ...
Sichen Meng, Shengwen Bao, Xiang Li, Shuaishuai Lu, Danfeng Ye, Ying Liu, Deli Sun, Hongwei Wu, Liangliang Zhu   +8 more
wiley   +1 more source

In vitro chloroquine resistance modulation study on fresh isolates of Brazilian Plasmodium falciparum: intrinsic antimalarial activity of phenothiazine drugs

Memorias do Instituto Oswaldo Cruz, 2002
Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian chloroquine-resistant fresh isolates of Plasmodium falciparum.
Carla MS Menezes, Karin Kirchgatter, Sílvia M Di Santi, Carine Savalli, Fabiola G Monteiro, Gilberto A Paula, Elizabeth I Ferreira   +6 more
doaj   +1 more source

Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens

Computational and Structural Biotechnology Journal, 2020
The status quo for combating uprising antibacterial resistance is to employ synergistic combinations of antibiotics. Nevertheless, the currently available combination therapies are fast becoming untenable.
Maytham Hussein, Xiaohan Hu, Olivia K.A. Paulin, Simon Crawford, Qi Tony Zhou, Mark Baker, Elena K. Schneider-Futschik, Yan Zhu, Jian Li, Tony Velkov   +9 more
doaj   +1 more source

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source