Results 61 to 70 of about 29,628 (301)
Aggregate, EarlyView.Reported herein is the rational‐designed aggregation‐induced emission molecule (BPT), its nanoparticles (BPT NPs), and further processed heat and peroxynitrite generating nanoplatform for precision multimodal imaging‐guided tumor phototherapy. This nanoplatform showed near‐infrared II fluorescence, photothermal, and photoacoustic imaging capabilities ...
Ziyi Xu +14 more
wiley +1 more source
Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines
Revista de Ciências Farmacêuticas Básica e Aplicada, 2005 Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage to mitochondria, leading to the impairment of metabolic functions and apoptosis.
T. Rodrigues +4 more
doaj
An Insight Into the Potentiation Effect of Potassium Iodide on aPDT Efficacy
Frontiers in Microbiology, 2018 Antimicrobial photodynamic therapy (aPDT) is gaining a special importance as an effective approach against multidrug-resistant strains responsible of fatal infections. The addition of potassium iodide (KI), a non-toxic salt, is recognized to increase the
Cátia Vieira +6 more
doaj +1 more source
Novel non-neuroleptic phenothiazines inhibit Mycobacterium tuberculosis replication.
Journal of Antimicrobial Chemotherapy, 2014 OBJECTIVES Phenothiazines are a commercially available class of psychotropic drugs known to show antituberculosis activity. At clinically relevant bactericidal doses, however, the psychotropic drugs produce undesirable side effects in addition to their ...
Sumayah Salie +4 more
semanticscholar +1 more source
Asian Journal of Organic Chemistry, EarlyView.Phenazinone chromophore incorporating a carbonyl group into the skeleton is recently found to be a new‐type halogen‐atom‐free‐photosensitizer possessing superior ability in singlet oxygen (1O2) generation. In this work, we have designed and developed the derivative with two 5‐formyl‐2‐thienyl substituents which is expected to lead to improvement of the
Hiroto Tsuyama +2 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2016 The pseudo five-component Sonogashira–Glaser cyclization synthesis of symmetrically 2,5-diaryl-substituted thiophenes is excellently suited to access thienyl-bridged oligophenothiazines in a one-pot fashion. Three thienyl-bridged systems were intensively
Dominik Urselmann +3 more
doaj +1 more source
<b> Photo-oxidative damage to isolated rat liver mitochondria induced by phenothiazines </b>
Revista de Ciências Farmacêuticas Básica e Aplicada, 2009 <p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: normal; text-align: justify; mso-layout-grid-align: none;"> Photosensitization is a well-known side-effect of phenothiazines that could involve photochemically promoted oxidative damage ...
T. RODRIGUES +4 more
doaj
Memorias do Instituto Oswaldo Cruz, 2002 Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian chloroquine-resistant fresh isolates of Plasmodium falciparum.
Carla MS Menezes +6 more
doaj +1 more source
Antimicrobial Photodynamic Therapy in the Control of COVID-19
Antibiotics, 2020 Antimicrobial photodynamic therapy (aPDT), using well known, safe and cost-effective photosensitizers, such as phenothiazines, e.g., methylene blue (MB), or porphyrins, e.g., protoporphyrin-IX (PP-IX), might help to mitigate the COVID-19 either to ...
Adelaide Almeida +2 more
doaj +1 more source
Angewandte Chemie International Edition, Accepted Article.The field of visible light‐mediated photochemistry has experienced significant growth, leading to the development of a wide array of methodologies in synthetic organic chemistry. In particular, photocatalysis by using long‐wavelength light such as red and near‐infrared (NIR) light has garnered substantial attention recently.
Tong Zhang, Suman Pradhan, Shoubhik Das
wiley +1 more source