Results 131 to 140 of about 2,545,958 (345)

GLUCURONIDASE PHENOTYPES OF INBRED MOUSE STRAINS [PDF]

, 1968
Roger E. Ganschow, Kenneth Paigen
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Crown Lengthening Surgery in the Esthetic Area for Optimized Results: A Review with Surgical Recommendations

Surgeries
Background: Crown lengthening (CL) in esthetic areas has become a versatile procedure with applications in many clinical situations. Knowledge concerning different periodontal phenotypes, and the supracrestal tissue attachment (STA)—former biological ...
Sérgio Kahn, Walmir Júnio de Pinho Reis Rodrigues, Alexandra Tavares Dias, Rodrigo Resende, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes   +5 more
doaj   +1 more source

GENETIC INTERACTION IN RYE EXPRESSED AT THE CHROMOSOME PHENOTYPE [PDF]

, 1962
A. Lima-de-Faria
openalex   +1 more source

The senescence-associated secretory phenotype: the dark side of tumor suppression.

Annual Review of Pathology, 2010
Jean-Philippe Coppé, P. Desprez, A. Krtolica, J. Campisi   +3 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Theoretical Consequences of Truncation Selection Based on the Individual Phenotype [PDF]

, 1960
B Griffing
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Editorial: Endotyping and phenotyping prematurity and its complications

Frontiers in Pediatrics, 2023
Maria Pierro, Roy Philip, Laurent Renesme, Eduardo Villamor   +3 more
doaj   +1 more source

Evaluation prevalence of Rh system major antigens (D, C, c, E, e) and their phenotypes in blood donors of Golestan province, Iran [PDF]

Medical Laboratory Journal
Background: The understanding of blood group phenotypes is currently limited to the ABO and Rh blood group systems. This study aimed to determine the frequency of Rh system antigens (D, C, c, E, e) and the phenotypes of the system in blood donors ...
Seyed Sadegh Baniaghil, Fardin Balochi, Alireza Ahmadi   +2 more
doaj