Results 151 to 160 of about 2,449,755 (371)
Reliability and predictability of phenotype information from functional connectivity in large imaging datasets [PDF]
arXivOne of the central objectives of contemporary neuroimaging research is to create predictive models that can disentangle the connection between patterns of functional connectivity across the entire brain and various behavioral traits. Previous studies have shown that models trained to predict behavioral features from the individual's functional ...
arxiv
Secondary Phenotype Analysis in Ascertained Family Designs: Application to the Leiden Longevity Study [PDF]
arXiv, 2016 The case-control design is often used to test associations between the case-control status and genetic variants. In addition to this primary phenotype a number of additional traits, known as secondary phenotypes, are routinely recorded and typically associations between genetic factors and these secondary traits are studied too.
arxiv
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Genotype, Phenotype and Mating Behavior of Drosophila melanogaster [PDF]
, 1962 B. W. Geer, M. M. Green
openalex +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
High Throughput Phenotyping of Physician Notes with Large Language and Hybrid NLP Models [PDF]
arXivDeep phenotyping is the detailed description of patient signs and symptoms using concepts from an ontology. The deep phenotyping of the numerous physician notes in electronic health records requires high throughput methods. Over the past thirty years, progress toward making high throughput phenotyping feasible.
arxiv
ASSORTATIVE MATING BASED ON PHENOTYPE: I. TWO ALLELES WITH DOMINANCE [PDF]
, 1969 Francesco M. Scudo, Samuel Karlin
openalex +1 more source
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
AGRIVITA Journal of Agricultural Science, 2012 The main objective of this research was to study the diversity of maize inbred lines based on phenotypic characters and SSR markers. The research, which was conducted from February to June 2011, was divided into field and laboratory research for ...
Heri Kustanto +3 more
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