Results 281 to 290 of about 26,955,799 (314)
Some of the next articles are maybe not open access.
Cytogenetic genotype-phenotype studies: Improving genotyping, phenotyping and data storage
Cytogenetic and Genome Research, 2006High-resolution molecular cytogenetic techniques such as genomic array CGH and MLPA detect submicroscopic chromosome aberrations in patients with unexplained mental retardation. These techniques rapidly change the practice of cytogenetic testing. Additionally, these techniques may improve genotype-phenotype studies of patients with microscopically ...
Feenstra, I. +2 more
openaire +3 more sources
Integration of Omics and Phenotypic Data for Precision Medicine
2022Over the past two decades, biomedical research is moving toward a big-data-driven approach. The underlying causes of this transition include the ability to gather genetic or molecular profiles of humans faster, the increasing adoption of electronic health record (EHR) system, and the growing interest in linking omics and phenotypic data for analysis ...
Juan, Zhao, QiPing, Feng, Wei-Qi, Wei
openaire +2 more sources
The estimation of phenotype distributions from pedigree data
American Journal of Medical Genetics, 1980AbstractA method is described to estimate from pedigree data the probability density function of a quantitative phenotype, given a specific genotype. Theoretically, pedigrees of any size or complexity that are segregating for conditions of known Mendelian inheritance can be used.
Robin M. Winter, John M. Optiz
openaire +2 more sources
Striving for Semantics of Plant Phenotyping Data
2018Addressing the goal of the workshop, i.e. to bridge the gap between academic and industrial aspects in regard to scholarly data, we inspect the case of plant phenotyping data publishing. We discuss how the publishers could foster advancements in the field of plant research and data analysis methods by warranting good quality phenotypic data with ...
openaire +2 more sources
Phenotype Inference from Text and Genomic Data
2017We describe ProTraits, a machine learning pipeline that systematically annotates microbes with phenotypes using a large amount of textual data from scientific literature and other online resources, as well as genome sequencing data. Moreover, by relying on a multi-view nonnegative matrix factorization approach, ProTraits pipeline is also able to ...
Maria Brbic +5 more
openaire +2 more sources
Integrating Large-Scale Genotype and Phenotype Data
OMICS: A Journal of Integrative Biology, 2006With the completion of the Human Genome Project, a new emphasis is focusing on the sequence variation and the resulting phenotype. The number of data available from genomic studies addressing this relationship is rapidly growing. In order to analyze these data as a whole, they need to be integrated, aggregated and annotated in a timely manner.
Tina, Hernandez-Boussard +3 more
openaire +2 more sources
Descriptive Statistics of Data: Understanding the Data Set and Phenotypes of Interest
2013A good understanding of the design of an experiment and the observational data that have been collected as part of the experiment is a key pre-requisite for correct and meaningful preparation of field data for further analysis. In this chapter, I provide a guideline of how an understanding of the field data can be gained, preparation steps that arise ...
openaire +2 more sources
Lifestyle and Preventive Medical Epigenetics
Medical Epigenetics, 2021Mustapha Umar Imam +2 more
exaly