Results 71 to 80 of about 164,403 (310)

Genetic Variability, Correlation and Path-Coefficient Studies in Litchi (Litchi chinensis Sonn.) for Plant Growth, Panicle and Yield Attributes

open access: yesInternational Journal of Bio-resource and Stress Management, 2022
Studies were carried out in National Active Germplasm Site (NAGS) at ICAR-NRC on Litchi, Muzaffarpur, Bihar, India during 2018 and 2019 to find out the association between different characters and magnitude of association of different characters with ...
N. Lal   +6 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Estimation of genetic variability, heritability and genetic advance as percent mean in black turmeric (Curcuma caesia Roxb.) genotypes

open access: yesElectronic Journal of Plant Breeding
Genetic variability, heritability, and genetic advance were evaluated in 33 genotypes of black turmeric (Curcuma caesia Roxb.) to identify traits suitable for effective selection.
A.B. Mohan Kumar   +3 more
doaj   +1 more source

Response of polygenic traits under stabilising selection and mutation when loci have unequal effects [PDF]

open access: yes, 2015
We consider an infinitely large population under stabilising selection and mutation in which the allelic effects determining a polygenic trait vary between loci.
Jain, Kavita, Stephan, Wolfgang
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Genetic variability, correlation and path analysis in mango ginger (Curcuma amada ROXB.)

open access: yesElectronic Journal of Plant Breeding, 2022
The present investigation was carried out at the Research Farm, Department of Genetics and Plant Breeding, Navsari Agricultural University, Navsari, Gujarat during the kharif, 2018. Twelve different quantitative characters related to rhizome yield were
Raval Kalpesh*, R. K. Patel, Rajesh Panchal and K. G. Modha
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Characterisation of sweet stem sorghum genotypes for bio-ethanol production

open access: yesActa Agriculturae Scandinavica. Section B, Soil and Plant Science, 2018
In an effort to characterise and select promising sweet stem sorghum genotypes with enhanced biofuel productivity, the present study investigated phenotypic variability present among diverse sweet stem sorghum genotypes based on ethanol production and ...
Precious Mangena   +2 more
doaj   +1 more source

Variability, heritability and genetic advance for yield and quality components in interspecific F1 hybrids of cotton

open access: yesElectronic Journal of Plant Breeding, 2017
Assessment of genetic variability using appropriate parameters like phenotypic coefficient of variation (PCV), genotypic coefficient of variation (GCV), heritability (h2), and genetic advance (GA) are really necessary to start an efficient breeding ...
Isong Abasianyanga and, P. Amala Balu
doaj   +1 more source

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