Results 61 to 70 of about 513,197 (334)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

GENETIC STUDIES ON REPRODUCTIVE PERFORMANCE OF INDIGENOUS GOATS IN NORTHERN ODISHA [PDF]

open access: yesExploratory Animal and Medical Research, 2016
Data on the reproductive parameters of 622 does, sired by 28 bucks, born during the period of 3 years from 2012 to 2015 in 28 villages of three districts viz. Deogarh, Keonjhar and Balasore of Odisha, India were included in the present study.
S.Ray   +4 more
doaj  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Correlation and path coefficient analysis of polygenic traits of upland cotton genotypes grown in Zimbabwe

open access: yesCogent Food & Agriculture, 2020
Cotton is a very important crop that consists of traits with different associationship due to genetic and environmental factors. In order to determine the degree of association between seed cotton yield and important traits, a study was done using an ...
B. Chapepa   +3 more
doaj   +1 more source

Morphological Variation in Arabica Coffee (Coffea Arabica L.) Growing in North Sumatra Indonesia [PDF]

open access: yes, 2018
Genetic variation is important in plant breeding. However, information on the genetic variability of Arabica coffee especially in coffee field of North Sumatra was not yet available.
Malau, S. (Sabam)   +1 more
core  

Direct and indirect selection on flowering time, water-use efficiency (WUE, δ (13)C), and WUE plasticity to drought in Arabidopsis thaliana. [PDF]

open access: yes, 2014
Flowering time and water-use efficiency (WUE) are two ecological traits that are important for plant drought response. To understand the evolutionary significance of natural genetic variation in flowering time, WUE, and WUE plasticity to drought in ...
Juenger, Thomas E   +3 more
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

RESEARCH REGARDING THE EXISTENCE OF A PHENOTYPIC CORRELATION BETWEEN STERN LENGTH AND THE ARRIVAL TIME AT GROSSE-FOND PIGEON STOCK JAN AARDEN

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Specialty literature is presenting few data about the estimation of the phenotypic correlations at voyager pigeon. The present study is aiming to present a classic and simple method, accessible to any pigeon ameliorator.
D. DRONCA   +9 more
doaj  

Seleção precoce de maracujazeiro pelo uso da correlação entre dados de produção mensal e anual Early selection in passion fruit using correlation data between monthly and annual productivity

open access: yesPesquisa Agropecuária Brasileira, 2008
O objetivo deste trabalho foi determinar épocas de avaliação da produtividade e de componentes da produção que permitam selecionar precocemente genótipos superiores de maracujazeiro.
Leonardo Duarte Pimentel   +3 more
doaj   +1 more source

Improved Estimation of Phenotypic Correlations Using Summary Association Statistics

open access: yesFrontiers in Genetics, 2021
Estimating the phenotypic correlations between complex traits and diseases based on their genome-wide association summary statistics has been a useful technique in genetic epidemiology and statistical genetics inference.
Ting Li   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy