Results 61 to 70 of about 513,197 (334)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
GENETIC STUDIES ON REPRODUCTIVE PERFORMANCE OF INDIGENOUS GOATS IN NORTHERN ODISHA [PDF]
Data on the reproductive parameters of 622 does, sired by 28 bucks, born during the period of 3 years from 2012 to 2015 in 28 villages of three districts viz. Deogarh, Keonjhar and Balasore of Odisha, India were included in the present study.
S.Ray+4 more
doaj
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Cotton is a very important crop that consists of traits with different associationship due to genetic and environmental factors. In order to determine the degree of association between seed cotton yield and important traits, a study was done using an ...
B. Chapepa+3 more
doaj +1 more source
Morphological Variation in Arabica Coffee (Coffea Arabica L.) Growing in North Sumatra Indonesia [PDF]
Genetic variation is important in plant breeding. However, information on the genetic variability of Arabica coffee especially in coffee field of North Sumatra was not yet available.
Malau, S. (Sabam)+1 more
core
Direct and indirect selection on flowering time, water-use efficiency (WUE, δ (13)C), and WUE plasticity to drought in Arabidopsis thaliana. [PDF]
Flowering time and water-use efficiency (WUE) are two ecological traits that are important for plant drought response. To understand the evolutionary significance of natural genetic variation in flowering time, WUE, and WUE plasticity to drought in ...
Juenger, Thomas E+3 more
core +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Specialty literature is presenting few data about the estimation of the phenotypic correlations at voyager pigeon. The present study is aiming to present a classic and simple method, accessible to any pigeon ameliorator.
D. DRONCA+9 more
doaj
O objetivo deste trabalho foi determinar épocas de avaliação da produtividade e de componentes da produção que permitam selecionar precocemente genótipos superiores de maracujazeiro.
Leonardo Duarte Pimentel+3 more
doaj +1 more source
Improved Estimation of Phenotypic Correlations Using Summary Association Statistics
Estimating the phenotypic correlations between complex traits and diseases based on their genome-wide association summary statistics has been a useful technique in genetic epidemiology and statistical genetics inference.
Ting Li+4 more
doaj +1 more source