Results 71 to 80 of about 289,644 (264)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Phenotypic Matching Without Genetic Correlation in Dimorphic Legs of Bulb Mites
Ecology and EvolutionThe evolution of exaggerated structures used as weapons in male–male contests often drives correlated changes in traits that compensate for their costs or enhance their benefits.
Diego Solano‐Brenes +4 more
doaj +1 more source
Italian Journal of Animal Science, 2010 The objectives of this study were to estimate genetic parameters for testday milk, fat and protein yields, in Murrah buffaloes. In this study 4,757 complete lactations of Murrah buffaloes were analyzed.
A. Bignardi +6 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Genetic analysis of fertility traits of Holstein dairy cattle in warm and temperate climate
Acta Scientiarum: Animal Sciences, 2016 The edited data set for the estimation of heritability, genetic and phenotypic correlations of fertility traits contained up to 23,402 records from 10,894 cows calved between 2001 and 2015.
Rabie Rahbar +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The Indian Journal of Agricultural Sciences, 2016 A field experiment was conducted on six Gossypium arboreum genotypes for two successive cropping seasons from 2011-2012 to 2012-2013 at Central Institute for Cotton Research, Regional Station, Sirsa, Haryana, India.
S L AHUJA +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Agricultural Sciences, 2012 The aim of this research is to determine the relationship among yield and some yield components of dry bean using correlation and path coefficient analysis. The experiment was carried out in irrigated conditions during 2004-2005 and 2005-2006 at the East
Haluk Kulaz, Vahdettin Çiftçi
doaj