Results 71 to 80 of about 8,412,468 (340)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Phenotypic correlates of the working dog microbiome

npj Biofilms and Microbiomes, 2022
AbstractDogs have a key role in law enforcement and military work, and research with the goal of improving working dog performance is ongoing. While there have been intriguing studies from lab animal models showing a potential connection between the gut microbiome and behavior or mental health there is a dearth of studies investigating the microbiome ...
Hillary A. Craddock, Anastasia Godneva, Daphna Rothschild, Yair Motro, Dan Grinstein, Yuval Lotem-Michaeli, Tamar Narkiss, Eran Segal, Jacob Moran-Gilad   +8 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Genetic and phenotypic relationships among endocrine and traditional fertility traits and production traits in Holstein-Friesian dairy cows [PDF]

, 2002
The objective of this study was to estimate the heritability of a number of traditional and endocrine fertility traits in addition to d-56 predicted milk yield (MY56), and the genetic and phenotypic correlations between these traits.
Royal, M.D., Flint, A.P.F., Woolliams, John   +2 more
core  

Correlation between viral load and phenotypic markers.

, 2013
NDGs were isolated from the blood of HIV+ patients (n = 21) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry. Correlation between viral load and phenotypic markers was determined by a
Tom Cloke (102046), Shanthi Herath (123884), Manuel Modolell (59010), Graham Taylor (241206), Pascale Kropf (59011), Ingrid Müller (59004), Markus Munder (59009), Philip Bergin (455930)   +7 more
core   +1 more source

Inter-association and path coefficient analysis for yield and yield attributing traits in ash gourd [Benincasa hispida (Thunb) Cogn.]

Electronic Journal of Plant Breeding
Twenty nine genotypes of ash gourd (land races and released varieties) were evaluated during summer season (March to July) of 2022 and 2023. The main objective of the study was to evaluate the inter-associations among 15 yield and yield attributing ...
Hament Thakur* and Vijay Kumar
doaj   +1 more source

Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification

eLife, 2022
Systems genetics holds the promise to decipher complex traits by interpreting their associated SNPs through gene regulatory networks derived from comprehensive multi-omics data of cell types, tissues, and organs.
Zhanying Feng, Zhana Duren, Jingxue Xin, Qiuyue Yuan, Yaoxi He, Bing Su, Wing Hung Wong, Yong Wang   +7 more
doaj   +1 more source

Genotype–phenotype correlations in Marfan syndrome [PDF]

Heart, 2017
Marfan syndrome (MFS) is an autosomal dominant connective-tissue disorder associated with abnormalities of the cardiovascular, ocular and musculoskeletal systems. Aortopathy, manifest as thoracic aortic aneurysm (TAA) and dissection, is the major cause of morbidity and mortality. Most individuals with MFS carry mutations in the gene FBN1 .
Landis, Benjamin J., Veldtman, Gruschen R., Ware, Stephanie M.   +2 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Bauch_etal_data_Telomeres-and-phenotypic-quality-ProcRSocB

, 2013
Bauch_etal_data_Telomeres-and-phenotypic-quality ...
Peter H. Becker (2913659), Christina Bauch (3192042), Simon Verhulst (143968)   +2 more
core   +1 more source