Results 61 to 70 of about 289,644 (264)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Assessing genetic diversity and heritability of effective traits on the yield of chickpea (Cicer arietinum L.) under rainfed condition [PDF]

پژوهش‌های حبوبات ایران, 2017
Introduction Drought stress is one of the most important abiotic stresses in the world. Chickpea play very important role for human life in the developing countries.
sayyed Saeed Moosavi, Mohammad Reza Abdollahi, Farzad Kian-ersi, Davood Ahmadi-Dehrashid   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genotype/phenotype correlation in hereditary spherocytosis

Haematologica, 2008
Red blood cells are biconcave under physiological conditions but their shape changes when navigating narrow blood vessels or confined spaces in tissue and organs (such as the spleen). The ability of a red cell to maintain its discoid shape, elasticity and deformability in the circulation ...
IOLASCON, ACHILLE, Avvisati R.A.
openaire   +4 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Estimation of Genetic Parameters for Carcass and Meat Quality Traits Using Genomic Information in Yorkshire Pigs

Animals
Carcass and meat quality traits are critical in pig breeding and production. Estimating genetic parameters for these traits is a vital aspect of breeding engineering, as accurate genetic parameters are essential for estimating breeding values, predicting
Yangxun Zheng, Fuping Ma, Xitong Zhao, Yanling Liu, Quan Zou, Huatao Liu, Shujuan Li, Zipeng Zhang, Sen Yang, Kai Xing, Chuduan Wang, Xiangdong Ding   +11 more
doaj   +1 more source

Phenotypic Correlations Between Egg Quality Traits Amid the Laying Phase of Broiler Breeder Hens

Contemporary Agriculture, 2022
In order to determine phenotypic correlations between the quality traits of eggs from 41-week-old broiler breeder hens (Cobb 500), a total of 105 eggs suitable for incubation were analyzed using descriptive statistics and Pearson’s correlation ...
Vekić Marinko, Savić Đorđe, Jotanović Stoja   +2 more
doaj   +1 more source

Comprehensive genotype-phenotype correlation in lissencephaly

Quantitative Imaging in Medicine and Surgery, 2018
Malformations of cortical development (MCD) are a heterogenous group of disorders with diverse genotypic and phenotypic variations. Lissencephaly is a subtype of MCD caused by defect in neuronal migration, which occurs between 12 and 24 weeks of gestation.
Ai Peng, Tan, Wui Khean, Chong, Kshitij, Mankad   +2 more
openaire   +3 more sources