Results 71 to 80 of about 536,745 (332)
Cogent Food & Agriculture, 2020 Cotton is a very important crop that consists of traits with different associationship due to genetic and environmental factors. In order to determine the degree of association between seed cotton yield and important traits, a study was done using an ...
B. Chapepa +3 more
doaj +1 more source
Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism. [PDF]
, 2015 Iberian ham production includes both purebred (IB) and Duroc-crossbred (IBxDU) Iberian pigs, which show important differences in meat quality and production traits, such as muscle growth and fatness.
Ayuso, Miriam +12 more
core +4 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Most of the genetic covariation between major depressive and alcohol use disorders is explained by trait measures of negative emotionality and behavioral control [PDF]
, 2016 Background Mental health disorders commonly co-occur, even between conceptually distinct syndromes, such as internalizing and externalizing disorders.
Ellingson, J. M +4 more
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Genotype/phenotype correlation in hereditary spherocytosis
Haematologica, 2008 Red blood cells are biconcave under physiological conditions but their shape changes when navigating narrow blood vessels or confined spaces in tissue and organs (such as the spleen). The ability of a red cell to maintain its discoid shape, elasticity and deformability in the circulation ...
IOLASCON, ACHILLE, Avvisati R.A.
openaire +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Turkish Journal of Agriculture: Food Science and TechnologyWheat is one of the most important crops all over the world in terms of yield, production, consumption, cultivation, and adoptability. Wheat genotypes exhibiting different yield associated traits which influence each other in many ways.
Akbar Ali +4 more
doaj +1 more source
Italian Journal of Animal Science, 2010 The objectives of this study were to estimate genetic parameters for testday milk, fat and protein yields, in Murrah buffaloes. In this study 4,757 complete lactations of Murrah buffaloes were analyzed.
A. Bignardi +6 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source