Results 81 to 90 of about 4,546,004 (334)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Genetic parameters estimates for milk, fat and protein yield analyzed by test day models for Murrah buffaloes in Brazil

Italian Journal of Animal Science, 2010
The objectives of this study were to estimate genetic parameters for testday milk, fat and protein yields, in Murrah buffaloes. In this study 4,757 complete lactations of Murrah buffaloes were analyzed.
A. Bignardi, H. Tonhati, L. Seno, R. Sesana, A. Tanaka, L. Albuquerque, R. Aspilcueta-Borquis   +6 more
doaj   +1 more source

Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification

eLife, 2022
Systems genetics holds the promise to decipher complex traits by interpreting their associated SNPs through gene regulatory networks derived from comprehensive multi-omics data of cell types, tissues, and organs.
Zhanying Feng, Zhana Duren, Jingxue Xin, Qiuyue Yuan, Yaoxi He, Bing Su, Wing Hung Wong, Yong Wang   +7 more
doaj   +1 more source

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

European Respiratory Journal, 2017
A clear understanding of the genetic basis of antibiotic resistance in Mycobacterium tuberculosis is required to accelerate the development of rapid drug susceptibility testing methods based on genetic sequence.
P. Miotto, B. Tessema, E. Tagliani, L. Chindelevitch, Angela M. Starks, C. Emerson, D. Hanna, P. Kim, R. Liwski, M. Zignol, C. Gilpin, S. Niemann, C. Denkinger, Joy Fleming, R. Warren, D. Crook, J. Posey, S. Gagneux, S. Hoffner, C. Rodrigues, I. Comas, D. Engelthaler, M. Murray, D. Alland, L. Rigouts, C. Lange, K. Dheda, R. Hasan, U. Ranganathan, R. McNerney, M. Ezewudo, D. Cirillo, M. Schito, C. Köser, T. Rodwell   +34 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Effect of intra row spacings on estimates of phenotypic and genotypic correlation coefficients in cotton (Gossypium arboreum)

The Indian Journal of Agricultural Sciences, 2016
A field experiment was conducted on six Gossypium arboreum genotypes for two successive cropping seasons from 2011-2012 to 2012-2013 at Central Institute for Cotton Research, Regional Station, Sirsa, Haryana, India.
S L AHUJA, D MONGA, R A MEENA, RISHI KUMAR, NEHA SAXENA   +4 more
doaj   +1 more source

Association studies with direct and indirect effects among different morpho-bio traits in Gossypium arboreum

Electronic Journal of Plant Breeding, 2021
The experiment was carried out at the Research Area of Cotton Section and Biochemistry Laboratory, Department of Genetics and Plant Breeding, CCSHAU, Hisar (Haryana, India) during kharif 2017-18. The observations were recorded for different morphological
Pooja, Omender Sangwan, S.R Pundir, Meenakshi Rathi* and Shivani Mandhania
doaj   +1 more source

Early‐life patterns of growth are linked to levels of phenotypic trait covariance and postfledging mortality across avian species

Ecology and Evolution, 2021
Life history studies have established that trade‐offs between growth and survival are common both within and among species. Identifying the factor(s) that mediate this trade‐off has proven difficult, however, especially at the among‐species level.
Loren Merrill, Todd M. Jones, Jeffrey D. Brawn, Michael P. Ward   +3 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Relationship Between Hygienic Behavior and Varroa destructor Mites in Colonies Producing Honey or Royal Jelly

Sociobiology, 2014
Genetic and phenotypic parameters for hygienic behavior, invasion and infestation rates, total and effective reproduction of Varroa destructor in Africanized honeybee colonies producing honey (20 hives) or royal jelly (30 mini-hives) were analyzed.
Maria Claudia Colla Ruvolo-Takasusuki, Vagner Alencar Toledo, Denise Alves Lopes   +2 more
doaj   +1 more source