Results 191 to 200 of about 192,777 (261)

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Accurate plant 3D reconstruction and phenotypic traits extraction via stereo imaging and multi-view point cloud alignment. [PDF]

Front Plant Sci
Wang Z, Zhang H, Bian L, Zhou L, Ge Y.
europepmc   +1 more source

Amcinonide Exhibits Antitumor Effects in Radioresistant Colorectal Cancer Through the circRNF10/miR‐296‐5p/Snail Axis

Advanced Science, EarlyView.
Amcinonide (AMC), the FDA‐approved corticosteroid, was identified as a repurposed agent for radiation‐resistant colorectal cancer. AMC suppresses radiation‐induced epithelial–mesenchymal transition, migration, and invasion via the circRNF10/miR‐296‐5p/Snail axis.
Hyun Jeong Seok, Dong Hyeon Lee, Junhye Kwon, Ui Sup Shin, In Hwa Bae   +4 more
wiley   +1 more source

Genetic diversity and population structure of Kudouzi (<i>Sophora alopecuroides</i>) in Northwest China revealed by SNP markers and seed phenotypic traits. [PDF]

Front Plant Sci
Luo C, Ma F, Niu P, Zhang Z, Chen W, Jiang P, Wang M, Chu G, Huang X.   +8 more
europepmc   +1 more source

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

Advanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu, Le Liu, Mengli Yu, Yuling Guo, Junli Ye, Jun Zhang, Rumeng Zhao, Jiajie Yang, Wanneng Yang, Yameng Xu, Liqiang Fan, Zuoren Yang   +11 more
wiley   +1 more source

Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets. [PDF]

Commun Biol
Koblitz J, Reimer LC, Pukall R, Overmann J.   +3 more
europepmc   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

Advanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu, Xiyu Zhao, Zheyi Jiang, Chaoliang Wen, Chaoyi Wang, Qiulian Wang, Qiang Huang, Fangren Lan, Shenghui Wu, Junying Li, Congjiao Sun, Huadong Yin, Ning Yang   +12 more
wiley   +1 more source

Genetic diversity analysis of proso millet (<i>Panicum miliaceum</i> L.) germplasm resources based on phenotypic traits and SSR markers. [PDF]

Front Plant Sci
Lv Z, Yang Y, Hou H, Yang S, Cui Z, Zhang X, Li J, Yuan Y, Liu M, Feng B.   +9 more
europepmc   +1 more source

Advancing European Plant Variety Registration: Data‐Driven Insights and Stakeholder Perspectives

Agribusiness, EarlyView.
ABSTRACT Efficient plant variety registration is crucial for fostering innovation in the European Union, yet the current regulatory framework is complex and faces calls for reform. This study provides data‐driven evidence to inform the ongoing legislative debate by employing a mixed‐methods approach.
Sergio Urioste Daza, Ibtissem Taghouti, José María Gil Roig   +2 more
wiley   +1 more source