Results 171 to 180 of about 2,617,089 (305)

Experimental dissection of phenotypic variation for quantitative disease resistance in canola (Brassica napus) - Leptosphaeria maculans interactions. [PDF]

Pest Manag Sci
Barrett LG, Zakeel MC, Van der Wouw AP, Maher R, Lindbeck KD, Sprague SJ.   +5 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Longitudinal Epigenetic Variation and Phenotypic Diversity Among the Efik People of Cross River State, Nigeria [PDF]

The paper deals with the Longitudinal Epigenetic Variation and Phenotypic Diversity Among the Efik People of Cross River State ...
Osim Peace Bassey
core  

Is Tori seeing red? A lesson for first-year biology that unveils the complexity of phenotypic variation with pedigree analysis. [PDF]

J Microbiol Biol Educ
Mohammed Kamal A, Choi S-a, Colynn A, Wood A, Steinwand BJ, Kalas P.   +5 more
europepmc   +1 more source

The International Variation in Asthma Phenotypes

Allergy, Asthma & Immunology Research
Maldonado-Puebla, Martin, Cardet, Juan Carlos   +1 more
openaire   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Phenotypic variation and genetic architecture of seedling salt tolerance in Xinjiang wheat revealed by GWAS and resequencing. [PDF]

Front Plant Sci
Fan G, Huang JN, Wang HJ, Ding Y, Gao Y, Tuhexun T, Ullah U, Wang Z, Khan L, Shalmani A, Fang H, Huang T.   +11 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Phenotypic variation in plants

, 2017
Besides genetics, also epigenetics can play a role in shaping the characteristics of a plant (phenotype). Epigenetics refers to chemical modifications of DNA and proteins associated with the DNA that can influence gene activity (the ‘epigenome’) and can be passed on through cell divisions and following generations.This thesis aimed to explore ...
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source