Results 1 to 10 of about 1,168,358 (338)
Phenotyping Cardiogenic Shock [PDF]
Journal of the American Heart Association, 2021 Background Cardiogenic shock (CS) is a heterogeneous syndrome with varied presentations and outcomes. We used a machine learning approach to test the hypothesis that patients with CS have distinct phenotypes at presentation, which are associated with ...
E. Zweck +23 more
semanticscholar +7 more sources
Insulin Resistance: From Mechanisms to Therapeutic Strategies [PDF]
Diabetes & Metabolism Journal, 2022 Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological levels of insulin.
Shin-Hae Lee +2 more
doaj +1 more source
Journal of Cardiovascular Development and Disease, 2022 There is increasing recognition of the value of four-dimensional flow cardiovascular magnetic resonance (4D-flow MRI) as a potential means to detect and measure abnormal flow behaviour that occurs during early left ventricular (LV) dysfunction.
Jiaxing Jason Qin +4 more
doaj +1 more source
Intensive Care Medicine, 2023 The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies ...
G. Grasselli +63 more
semanticscholar +1 more source
Nucleic Acids Res., 2022 The International Mouse Phenotyping Consortium (IMPC; https://www.mousephenotype.org/) web portal makes available curated, integrated and analysed knockout mouse phenotyping data generated by the IMPC project consisting of 85M data points and over 95,000
T. Groza +16 more
semanticscholar +1 more source
Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease
bioRxiv, 2021 Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as Alzheimer’s disease in which numerous models are being generated, a challenging first step is to ...
S. Forner +20 more
semanticscholar +1 more source
Relevance of body composition in phenotyping the obesities
Reviews in Endocrine & Metabolic Disorders, 2023 Obesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia.
Laura Salmón-Gómez +3 more
semanticscholar +1 more source
Biology, 2023 Simple Summary The future of plant biology, particularly rapidly advancing precision horticulture and predictive breeding, will require the transformation of huge volumes of multi-omics data into structured information and valuable knowledge ...
D. Cembrowska-Lech +7 more
semanticscholar +1 more source
Scientific Reports, 2021 Given the rapid increase in the incidence of cardiometabolic conditions, there is an urgent need for better approaches to prevent as many cases as possible and move from a one-size-fits-all approach to a precision cardiometabolic prevention strategy in ...
Guy Fagherazzi +10 more
doaj +1 more source
Current Opinion in Hematology, 2012 Although recorded evidence of phenotyping bleeding disorders extends back two millennia, standardization of phenotyping has only begun in the past half century. This was spurred by the need for greater precision in diagnosing disorders in order to select proper laboratory tests and treatment, and the realization that the bleeding history provides ...
Paula, James, Barry S, Coller
openaire +2 more sources