Results 111 to 120 of about 253,606 (273)

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. [PDF]

, 2019
[This corrects the article DOI: 10.1038/s42003-018-0226-0.]
Adissu, Hibret, Asomugha, Chinwe, Beaudet, Arthur L, Berberovic, Zorana, Bohat, Ritu, Bower, Lynette, Braun, Robert E, Brown, Steve DM, Cater, Heather, Clary, David, Clementson-Mobbs, Sharon, Cooper, Ann, de Angelis, Martin Hrabe, Dickinson, Mary E, Edwards, Sydney G, Eskandarian, Mohammed, Flenniken, Ann M, Fletcher, Colin, Flicek, Paul, Gallegos, Juan J, Gao, Xiang, Griffey, Stephen M, Heaney, Jason D, Herault, Yann, Hsu, Chih-Wei, Imai, Denise M, International Mouse Phenotyping Consortium, Joynson, Russell, Justice, Monica J, Kalaga, Sowmya, Karp, Natasha, Kent Lloyd, KC, Krebs, Mark P, Kumar, Vivek, Leonard, Brian C, Mallon, Ann-Marie, Mason, Jeremy, McKerlie, Colin, Meehan, Terrence F, Meziane, Hamid, Moore, Bret A, Moore, Mark, Moshiri, Ala, Murphy, Christopher J, Murray, Stephen A, Newbigging, Susan, Nishina, Patsy M, Nutter, Lauryl MJ, Owen, Celeste, Parkinson, Helen, Philip, Vivek, Ramirez-Solis, Ramiro, Reilly, Christopher, Roux, Michel J, Santos, Luis, Seavitt, John R, Sebbag, Lionel, Seong, JK, Smedley, Damian, Stewart, Michelle, Straiton, Ewan, Suzuki, Tomohiro, Svenson, Karen L, Thomasy, Sara M, Tocchini-Valentini, Glauco, Udensi, Uchechukwu, Wakana, Shigeharu, Wells, Sara, White, Jacqueline K, Wurst, Wolfgang   +69 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Genetic diversity and population structure of a core collection of Mediterranean durum wheat accessions using DArTseq markers

BMC Genomics
Background Durum wheat was domesticated in the Fertile Crescent and later spread to the Mediterranean, where human and natural selection led to the establishment of local landraces.
Marwa Laribi, Sarrah Ben M’Barek, Sandra M. Velasco-Cuervo, Sheau-Fang Hwang, Amor H. Yahyaoui, Stephen E. Strelkov   +5 more
doaj   +1 more source

Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study

Research
Metabolic dysfunction-associated steatohepatitis (MASH) is the progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD), and closely associated with a high risk of liver-related morbidity and mortality.
Mengqi Fan, Erfei Song, Yuying Zhang, Pengfei Zhang, Bing Huang, Kaixuan Yan, Wah Yang, Subrata Chakrabarti, Hema Mahajan, Sen Yan, Ying Xu, Shuang Hua, Wei Liu, Cunchuan Wang, Aimin Xu, Dewei Ye   +15 more
doaj   +1 more source

Gombarezisztencia gének térképezése szőlőben = Mapping resistance genes against fungi in grapevine [PDF]

, 2010
Lisztharmat (PM) és peronoszpóra (DM) rezisztencia génekkel kapcsolt markerek szelekcióra való alkalmasságát vizsgáltuk szőlő inter-és intraspecifikus térképezési populációiban.
Galli, Zsolt, Halász, Gábor, Heszky, László, Hoffmann, Sarolta, Kiss, Erzsébet, Kozma, Pál, Szoke, Antal, Veres, Anikó   +7 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Phenotyping on microscopic scale using DIC microscopy [PDF]

, 2014
Image analysis of Arabidopsis (Arabidopsis thaliana) plants is an important method for studying plant growth. Most work on automated analysis focuses on full rosette analysis, often in a high-throughput monitoring system.
De Vylder, Jonas, Dhondt, Stijn, Inzé, Dirk, Luong, Hiep, Philips, Wilfried   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Trajectories of persisting Covid- 19 symptoms up to 24 months after acute infection: findings from the Predi-Covid cohort study

BMC Infectious Diseases
Introduction Long COVID is a multisystemic, fluctuating condition inducing a high burden on affected people. Despite the existence of some guidelines, its management remains complicated.
Aurélie Fischer, Lu Zhang, Abir Elbéji, Paul Wilmes, Chantal J. Snoeck, Jérôme Larché, Pauline Oustric, Markus Ollert, Guy Fagherazzi   +8 more
doaj   +1 more source

Groundnut (Arachis hypogaea L.) improvement in sub-Saharan Africa: a review

Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2019
Groundnut (Arachis hypogaea L.) is a multi-purpose legume crop widely cultivated in sub-Saharan Africa (SSA). However, yield levels of the crop has remained relatively low in SSA owing to a range of biotic, abiotic and socio-economic constraints.
Seltene Abady, Hussein Shimelis, Pasupuleti Janila, Jacob Mashilo   +3 more
doaj   +1 more source