Results 141 to 150 of about 1,264,213 (379)
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Animal, 2011 Lamb mortality remains a significant welfare and economic issue for sheep production. Lamb survival is to a degree dependent upon an easy delivery and the expression of appropriate behaviours from both mother and offspring, such as rapid standing, udder ...
S.M. Matheson +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
ResearchMetabolic dysfunction-associated steatohepatitis (MASH) is the progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD), and closely associated with a high risk of liver-related morbidity and mortality.
Mengqi Fan +15 more
doaj +1 more source
Phenotyping on microscopic scale using DIC microscopy [PDF]
, 2014 Image analysis of Arabidopsis (Arabidopsis thaliana) plants is an important method for studying plant growth. Most work on automated analysis focuses on full rosette analysis, often in a high-throughput monitoring system.
De Vylder, Jonas +4 more
core +1 more source
Leveraging Image Analysis for High-Throughput Plant Phenotyping
Frontiers in Plant Science, 2019 The complex interaction between a genotype and its environment controls the biophysical properties of a plant, manifested in observable traits, i.e., plant's phenome, which influences resources acquisition, performance, and yield.
Sruti Das Choudhury, A. Samal, T. Awada
semanticscholar +1 more source
Phenotype annotation with the ontology of microbial phenotypes (OMP)
Journal of Biomedical Semantics, 2019 Microbial genetics has formed a foundation for understanding many aspects of biology. Systematic annotation that supports computational data mining should reveal further insights for microbes, microbiomes, and conserved functions beyond microbes. The Ontology of Microbial Phenotypes (OMP) was created to support such annotation.We define standards for ...
Deborah A. Siegele +6 more
openaire +4 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source