Results 151 to 160 of about 135,840 (268)

AI-enabled digital phenotyping for Alzheimer's disease: a review of multimodal sensor integration and symptom trajectories. [PDF]

Alzheimers Res Ther
Kim SJ, Kim MJ, Kim JS, Jang J, Choi W, Lee HJ, Song JH, Hoe HS.   +7 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Applicability of the StatFaRmer time series analysis tool in soybean (Glycine max) digital phenotyping. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Ulyanov DS, Ulyanova AA, Kocheshkova AA, Blinkov AO, Arkhipov AV, Meglitskaya YS, Svistunova NY, Karlov GI, Divashuk MG.   +8 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Advancing multi-scale plant phenotyping for precision agriculture and sustainable crop production. [PDF]

J Zhejiang Univ Sci B
Feng X, Li Z, Wang K.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Perceptual graph kernels for image-derived plant trait interaction analysis in precision agriculture. [PDF]

Front Plant Sci
S S, T R.
europepmc   +1 more source

Phenotype matters [PDF]

Nature Genetics, 2004
openaire   +2 more sources

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Advancements in 3D Reconstruction for Plant Phenotyping: Technologies, Applications, Challenges, and Future Directions. [PDF]

Sensors (Basel)
Ghose P, Bashir A, Zahid A.
europepmc   +1 more source