Results 171 to 180 of about 194,178 (304)

Digital Phenotyping in Health Research: Scoping Review of Methods, Gaps, and Opportunities. [PDF]

J Med Internet Res
Badier N, Lafitte A, Difernand A, Aguayo GA, Fagherazzi G, Onnela JP, Vittrant B, Lechat B, De Larochelambert Q, Toussaint JF, Delrieu L.   +10 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Computational Phenotyping of Obstructive Airway Diseases: A Systematic Review [PDF]

Muwada Bashir Awad Bashir,1 Gregorio Paolo Milani,2,3,* Valentina De Cosmi,4,5,* Alessandra Mazzocchi,3,* Guoqiang Zhang,1 Rani Basna,1 Linnea Hedman,6 Anne Lindberg,7 Linda Ekerljung,1 Malin Axelsson,8 Lowie EGW Vanfleteren,9 Eva Rönmark,6 ...
De Cosmi V, Zhang G, Hedman L, Lindberg A, Bashir MBA, Kankaanranta H, Ekerljung L, Milani GP, Mazzocchi A, Nwaru BI, Basna R, Vanfleteren LEGW, Backman H, Rönmark E, Axelsson M   +14 more
core  

Identification and reporting of heart failure with preserved ejection fraction in Sub-Saharan Africa: a scoping review of diagnostic approaches, echocardiographic assessment, and evidence gaps. [PDF]

Egypt Heart J
Adejumo FA, Olaniyan SG, Adejumo TP, Odunaro SK, Oba HA, Falope BJ, Kasali OE, Obielodan OO, Aderinto N.   +8 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Big data and psychiatry: advances, constraints and future directions. [PDF]

World Psychiatry
Stein DJ, Kessler RC, Torous J, Garavan H, van den Heuvel OA, Derks EM, Mathews C, Cuijpers P, Salum GA, Andreassen OA, Thompson PM, Penninx BWJ, McGrath JJ.   +12 more
europepmc   +1 more source

Phenotypes of Klotho

Aging, 2019
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Evaluation of the biodistribution of [^99mTc]Tc-PSMA-GCK01 SPECT/CT in a prospective, intraindividual comparison with [⁶⁸Ga]PSMA-11 PET/CT for phenotyping in mCRPC prior to PSMA-targeted radioligand therapy. [PDF]

EJNMMI Res
Novruzov E, Mamlins E, Kabunda J, Cardinale J, Qebetu M, Kratochwil C, Feisthauer A, Martlbauer S, Kaoma CA, Sibiya S, de Bruin T, Mdanda S, Shungube M, Davis C, Smith L, Mzizi Y, Mokoala K, Ndlovu H, Ramonaheng K, Giesel FL, Sathekge MM.   +20 more
europepmc   +1 more source