Results 11 to 20 of about 1,264,213 (379)

Insulin Resistance: From Mechanisms to Therapeutic Strategies [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological levels of insulin.
Shin-Hae Lee   +2 more
doaj   +1 more source

Evaluation of Left Ventricular Function Using Four-Dimensional Flow Cardiovascular Magnetic Resonance: A Systematic Review

open access: yesJournal of Cardiovascular Development and Disease, 2022
There is increasing recognition of the value of four-dimensional flow cardiovascular magnetic resonance (4D-flow MRI) as a potential means to detect and measure abnormal flow behaviour that occurs during early left ventricular (LV) dysfunction.
Jiaxing Jason Qin   +4 more
doaj   +1 more source

The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease

open access: yesNucleic Acids Res., 2022
The International Mouse Phenotyping Consortium (IMPC; https://www.mousephenotype.org/) web portal makes available curated, integrated and analysed knockout mouse phenotyping data generated by the IMPC project consisting of 85M data points and over 95,000
T. Groza   +16 more
semanticscholar   +1 more source

Relevance of body composition in phenotyping the obesities

open access: yesReviews in Endocrine & Metabolic Disorders, 2023
Obesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia.
Laura Salmón-Gómez   +3 more
semanticscholar   +1 more source

Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease

open access: yesbioRxiv, 2021
Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as Alzheimer’s disease in which numerous models are being generated, a challenging first step is to ...
S. Forner   +20 more
semanticscholar   +1 more source

An Integrated Multi-Omics and Artificial Intelligence Framework for Advance Plant Phenotyping in Horticulture

open access: yesBiology, 2023
Simple Summary The future of plant biology, particularly rapidly advancing precision horticulture and predictive breeding, will require the transformation of huge volumes of multi-omics data into structured information and valuable knowledge ...
D. Cembrowska-Lech   +7 more
semanticscholar   +1 more source

Image-Based High-Throughput Phenotyping in Horticultural Crops

open access: yesPlants, 2023
Plant phenotyping is the primary task of any plant breeding program, and accurate measurement of plant traits is essential to select genotypes with better quality, high yield, and climate resilience.
A. Abebe   +4 more
semanticscholar   +1 more source

Towards precision cardiometabolic prevention: results from a machine learning, semi-supervised clustering approach in the nationwide population-based ORISCAV-LUX 2 study

open access: yesScientific Reports, 2021
Given the rapid increase in the incidence of cardiometabolic conditions, there is an urgent need for better approaches to prevent as many cases as possible and move from a one-size-fits-all approach to a precision cardiometabolic prevention strategy in ...
Guy Fagherazzi   +10 more
doaj   +1 more source

Association between use of psychotropic medications prior to SARS-COV-2 infection and trajectories of COVID-19 recovery: Findings from the prospective Predi-COVID cohort study

open access: yesFrontiers in Public Health, 2023
Psychological disturbances are frequent following COVID-19. However, there is not much information about whether pre-existing psychological disorders are associated with the severity and evolution of COVID-19. We aimed to explore the associations between
Gloria A. Aguayo   +5 more
doaj   +1 more source

Using a global diversity panel of Cannabis sativa L. to develop a near InfraRed-based chemometric application for cannabinoid quantification

open access: yesScientific Reports, 2023
C. sativa has gained renewed interest as a cash crop for food, fibre and medicinal markets. Irrespective of the final product, rigorous quantitative testing for cannabinoids, the regulated biologically active constituents of C.
Francine Gloerfelt-Tarp   +6 more
doaj   +1 more source

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