Results 21 to 30 of about 113,403 (172)

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

The "plus" side of epilepsy phenotyping [PDF]

, 2017
No abstract ...
Striano, Pasquale, Zuberi, Sameer M.
core   +1 more source

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

The Universal Phenotype

, 2019
Organisms. Journal of Biological Sciences, V. 3, N. 2 (2019)
Alessio Martino, Alessandro Giuliani, Antonello Rizzi   +2 more
openaire   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

High throughput phenotyping methods for screening rice germplasm under water limited field conditions [PDF]

, 2010
A Cirad project (Orytage) involving NARS and IRC aims at developing an international phenotyping network for rice adaptations to drought and thermal stresses in the context of gene discovery and genetic mapping.
Audebert, Alain, Châtel, Marc, Grenier, Cécile, Ospina, Yolima, Rodriguez, Francisco   +4 more
core  

Challenges and opportunities for quantifying roots and rhizosphere interactions through imaging and image analysis [PDF]

, 2014
The morphology of roots and root systems influences the efficiency by which plants acquire nutrients and water, anchor themselves and provide stability to the surrounding soil. Plant genotype and the biotic and abiotic environment significantly influence
Abbas-Zadeh, Adu, al Hagrey, Amato, Armengaud, Asseng, Bailey, Balasubramanian, Baldwin, Bao, Barton, Basu, Bates, Batey, Bauer, Beemster, Bengough, Bengough, Bengough, Benjamin, Berendsen, Bingham, Bloemberg, Blossfeld, Blossfeld, Blossfeld, Blossfeld, Bohn, Bois, Bottomley, Bougourd, Bovina, Brady, Brooks, Brown, Bruand, Burton, Burton, Caldwell, Carminati, Carminati, Carminati, Chaparro, Chapman, Clark, Clark, Clark, Clark, Czarnes, Czymmek, Dai, Dannoura, Darwin, Dechamps, Delhaize, Delin, Den Herder, Dhondt, Dietrich, Dixit, Dong, Donner, Downie, Downie, Draye, Dubrovsky, Duncan, Ehlers, Eickhorst, Faget, Faget, Faget, Fang, Fang, Federici, Fiorani, Fisher, Frangi, French, French, Gage, Galkovskyi, Gamalero, Garbout, Gasch, Genre, George, Goh, Gomiero, Gregory, Gregory, Gregory, Grose, Grzesiak, Hainsworth, Haling, Hammond, Hamza, Hamza, Hapca, Harris, Haynes, Heeraman, Herrera, Hiltner, Houle, Hu, Huisken, Humphris, Hund, Ishikawa, Jahnke, Jassogne, Johnson, Kaestner, Kell, Ketcham, Keyes, King, Kiser, Kreike, Kuchenbuch, Kutschera, Lambers, Lebreton, Lee, Lind, Lobet, Lobet, Lontoc-Roy, Lopez-Bucio, Loudet, Luster, Lynch, Macfall, Macfall, Mairhofer, Maizel, Martino, McKenzie, Metscher, Mir, Mooney, Moradi, Moradi, Moter, Mullen, Nagel, Neumann, Nonomura, Okumoto, Ortiz-Ribbing, Osmont, Oswald, Perret, Pierret, Pierret, Pierret, Pohlmeier, Poon, Ray, Reddy, Redjala, Reynolds, Roberts, Rochat, Rogers, Rudolph, Rudolph, Saini, Santi, Santner, Schmidt, Segal, Sena, Sezgin, Sharpe, Shi, Smit, Spohn, Stromberg, Tan, Thorisson, Tilman, Trachsel, Tracy, Tracy, Tracy, Tracy, Tsaftaris, Tumlinson, Vacheron, Valentine, Valentine, Valentine, Valentine, Veen, Villordon, Vollsnes, Walter, Walter, Wang, Watt, Watt, Watt, Weele, Wells, White, White, White, Wildenschild, Willatt, Willatt, Willatt, Wojciechowski, Wu, Wuyts, Yang, Zappala, Zhang, Zhu   +220 more
core   +3 more sources