Results 31 to 40 of about 1,098 (175)

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Impact of Intermediate Wheatgrass as an Adjunct Ingredient on the Chemical Composition and Development of Aroma Compounds in Sake Brewing

Cereal Chemistry, Volume 103, Issue 5, Page 695-706, September/October 2026.
ABSTRACT Background Replacing a portion of polished rice with intermediate wheatgrass (IWG) could diversify raw materials for sake, but its effects on composition and fermentation outcomes are not well characterized. The objective of this study was to quantify how adjunct form (whole vs.
Takehiro Murai, Curtis Payne, George Amponsah Annor   +2 more
wiley   +1 more source

Synthesis of phenylacetic acid regioisomers possessing an N-substituted 1,2-dihydropyrid-2-one pharmacophore — Evaluation as inhibitors of cyclooxygenases and 5-lipoxygenase

, 2011
The Suzuki–Miyaura cross-coupling reaction provides a useful method for the synthesis of methyl 2-(2-chloropyridyl or 2-methoxypyridyl)phenylacetates. The 2-chloropyridyl or 2-methoxypyridyl ring system can be readily elaborated to N-substituted (OH, Me,
Morshed A. Chowdhury, Gang Yu, Khaled R. A. Abdellatif, Zhangjian Huang, Edward E. Knaus   +4 more
core   +1 more source

Structure‐Guided Optimization of a Molecular Glue Targeting the KBTBD4‐HDAC1/2 Complex

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Structure‐based optimization of the molecular glue degrader UM171 resulted in a near 20‐fold improvement of ternary complex stability but also revealed the challenges of glue discovery. Optimization of UM171, a molecular glue initiating the degradation of neosubstrate HDAC1/2–CoREST–LSD1 through a multiprotein complex formed with KBTBD4, was carried ...
Timea Balo, Zhuoyao Chen, Laurine Palluaud, Arpad Kiss, Tibor Novak, Andras Herner, Alex N. Bullock, Virginie Martiny, Andras Kotschy   +8 more
wiley   +1 more source

Pd‐Catalyzed Direct Access to 2‐Substituted (Aza)benzo[b]furans via Cascade Reactions Under “On‐Water” Conditions

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An “on‐water” scalable Pd‐catalyzed heteroannulation delivers benzofurans and furopyridines at ultralow catalyst loadings (down to 0.005 mol%), providing products essentially free of palladium residues. In addition to a broad substrate scope (aryl, alkenyl, and alkyl alkynes with o‐iodophenols or 2‐iodo‐3‐hydroxypyridines), this protocol enables a new ...
Iratxe Astarloa, María Teresa Herrero, Garazi Urgoitia, Raul SanMartin   +3 more
wiley   +1 more source

Identification of Volatile Odor Compounds in Extracts of Four Types of Herbaceous Plant Spices via GC × GC–O‐TOF MS

eFood, Volume 7, Issue 4, August 2026.
In this study, sensory evaluation, electronic nose, solid‐phase microextraction, and comprehensive two‐dimensional gas chromatography‐olfactometry‐time‐of‐flight mass spectrometry were used to analyze the volatile compounds and key odor‐active components in the extracts of sour horn, alfalfa, chicory, and fenugreek, and a total of 59 odor‐active ...
Suxing Tuo, Qinghui Jia, Shuang Bi, Yixin Dai, Ting Deng, Hongbing Lu, Jiaxiao Cai, Zifeng Li, Cheng Yang, Kejun Zhong, Bo Kong, Ye Liu   +11 more
wiley   +1 more source

Ultrasonic enhancement of electrochemiluminescence from arylacetate electrooxidation

, 1994
This paper describes the previously unreported electrogenerated chemiluminescence (ECL) from the electro-oxidation of several aryl carboxylates at a platinum flag electrode in aqueous, methanolic and acetonitrile solutions using tetramethylammonium ...
Richards, P., Clarke, L., Colton, D., Phull, S.S., Javed, T., Chyla, A., Lorimer, J.P., Mason, T.J.; id_orcid, Walton, D.J.   +8 more
core   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, Volume 5, Issue 4, August 2026.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

A versatile synthesis of cyclic dipeptides using the stepwise construction of the piperazine-2,5-dione ring from simple precursors: synthetic sequence and the structure of a representative product, (3RS)-4-(2-allyl-3,5-dimethylphenyl)-1-benzyl-3-phenylpiperazine-2,5-dione

, 2018
A versatile synthesis of multiply substituted cyclic dipeptides has been designed, based on the stepwise construction of the piperazine-2,5-dione ring using molecular fragments from four different precursor molecules.
Christopher Glidewell, Lina M. Acosta Quintero, Alirio Palma, Justo Cobo   +3 more
core   +1 more source

Diversity of flies visiting and pollinating flowers of the Southern African genus Riocreuxia (Apocynaceae: Ceropegieae, Anisotominae)

TAXON, Volume 75, Issue 4, August 2026.
Abstract The subtribe Stapeliinae (Apocynaceae: Asclepiadoideae) contains ca. 720 species and, with fly pollination being ubiquitous in the group, appears to have diversified without shifts between major groups of pollinators. In contrast, the sister subtribe Anisotominae, which only has ca.
Annemarie Heiduk, Andrew Whittington, Frank Menzel, Esben Bøggild, Jean‐Paul Haenni, Michael von Tschirnhaus, John Mark Hash, Steven D. Johnson, Adam Shuttleworth   +8 more
wiley   +1 more source