Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
A Gil-Izquierdo +53 more
core +3 more sources
Comparative genomic analyses reveal a lack of a substantial signature of host adaptation in Rhodococcus equi (‘Prescottella equi’) [PDF]
Rhodococcus equi (‘Prescottella equi’) is a pathogenic actinomycete primarily infecting horses but has emerged as an opportunistic human pathogen. We have sequenced the genome of the type strain of this species, R.
Arruda +35 more
core +1 more source
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Phenylacetic Acid (3S,6S)-6-Acetoxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl Ester
n ...
Yang Lu, Yin-Yao Niu
doaj +1 more source
Crystallographic and spectroscopic characterization of (R)-O-acetylmandelic acid
The title compound [systematic name: (R)-(−)-2-acetoxy-2-phenylacetic acid], C10H10O4, is a resolved chiral ester derivative of mandelic acid. The compound contains an acetate group and a carboxylic acid group, which engage in intermolecular hydrogen ...
Cady Cirbes, Joseph M. Tanski
doaj +1 more source
Photocatalyzed radiosynthesis of 11C‐phenylacetic acids
Fast and straightforward incorporation of radionuclides into pharmaceutically relevant molecules is one of the main barriers to preclinical and clinical tracer research. Late‐stage direct incorporation of cyclotron‐produced [11C]CO2 to afford carbon‐11‐labeled radiopharmaceuticals has the potential to provide ready‐to‐inject positron emission ...
Maxime Munch +3 more
openaire +2 more sources
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3 [PDF]
Here we report that an engineered microbial cytochrome P450 BM-3 (CYP102A subfamily) efficiently catalyzes the α-hydroxylation of phenylacetic acid esters.
Arnold, Frances H. +5 more
core +2 more sources
The phenylacetic acid (PA) degradative pathway is the central pathway by which complex aromatic compounds (e.g. styrene) get degraded. Upper pathways for different aromatic compounds converge at common intermediate phenylacetyl-CoA, which is then ...
Ijeme A Imolorhe, Silvia T Cardona
doaj +1 more source
A novel Ba(II) complex, [BaL2Cl2] (1) (L = pyridine-2-carboxaldehyde-2-phenylacetic acid hydrazone), has been synthesized using BaCl2, pyridine-2-carboxaldehyde and 2-phenylacetohydrazide as raw materials.
Li-Hua Wang +3 more
doaj +1 more source
Moderate intake of red wine promotes a significant increase of phenolic metabolites in human faeces [PDF]
With the final aim of ascertaining consistent data about the changes of phenolic metabolites in faeces after a regular wine consumption, the present paper compiles the data from two previous human intervention studies: a) a pilot study (n = 8), that ...
Bartolomé, Begoña +4 more
core +1 more source

